Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Schnabel, Annegret | - |
| dc.creator | Blois, Sandra M. | - |
| dc.creator | Meint, Peter | - |
| dc.creator | Freitag, Nancy | - |
| dc.creator | Ernst, Wolfgang | - |
| dc.creator | Barrientos, Gabriela Laura | - |
| dc.creator | Conrad, Melanie L. | - |
| dc.creator | Rose, Matthias | - |
| dc.creator | Seelbach-Göbel, Birgit | - |
| dc.date | 2018-05-03T17:08:51Z | - |
| dc.date | 2018-05-03T17:08:51Z | - |
| dc.date | 2016-04 | - |
| dc.date | 2018-05-03T13:57:04Z | - |
| dc.date.accessioned | 2019-04-29T15:26:15Z | - |
| dc.date.available | 2019-04-29T15:26:15Z | - |
| dc.date.issued | 2016-04 | - |
| dc.identifier | Schnabel, Annegret; Blois, Sandra M.; Meint, Peter; Freitag, Nancy; Ernst, Wolfgang; et al.; Elevated systemic galectin-1 levels characterize HELLP syndrome.; Elsevier Ireland; Journal of Reproductive Immunology; 114; 4-2016; 38-43 | - |
| dc.identifier | 0165-0378 | - |
| dc.identifier | http://hdl.handle.net/11336/43966 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/294163 | - |
| dc.description | Galectin-1 (gal-1), a member of a family of conserved β-galactoside-binding proteins, has been shown to exert a key role during gestation. Though gal-1 is expressed at higher levels in the placenta from HELLP patients, it is still poorly understood whether systemic gal-1 levels also differ in HELLP patients. In the present study, we evaluated the systemic expression of gal-1, together with the angiogenic factors, placental growth factor (PlGF) and soluble fms-like tyrosine kinase 1 (sFlt-1) in conjunction with HELLP syndrome severity. Systemic levels of gal-1 and sFlt-1 were elevated in patients with both early- and late-onset HELLP syndrome as compared to healthy controls. In contrast, peripheral PlGF levels were decreased in early- and late-onset HELLP. A positive correlation between systemic gal-1 levels and sFlt-1/PlGF ratios was found in early onset HELLP patients. Our results show that HELLP syndrome is associated with increased circulating levels of gal-1; integrating systemic gal-1 measurements into the diagnostic analyses of pregnant women may provide more effective prediction of HELLP syndrome development | - |
| dc.description | Fil: Schnabel, Annegret. Universitat Regensburg; Alemania | - |
| dc.description | Fil: Blois, Sandra M.. Charité-Universitätsmedizin Berlin; Alemania | - |
| dc.description | Fil: Meint, Peter. Universitat Regensburg; Alemania | - |
| dc.description | Fil: Freitag, Nancy. Charité-Universitätsmedizin Berlin; Alemania | - |
| dc.description | Fil: Ernst, Wolfgang. Universitat Regensburg; Alemania | - |
| dc.description | Fil: Barrientos, Gabriela Laura. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Charité-Universitätsmedizin Berlin; Alemania | - |
| dc.description | Fil: Conrad, Melanie L.. Charité-Universitätsmedizin Berlin; Alemania | - |
| dc.description | Fil: Rose, Matthias. Charité-Universitätsmedizin Berlin; Alemania | - |
| dc.description | Fil: Seelbach-Göbel, Birgit. Universitat Regensburg; Alemania | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Elsevier Ireland | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.jri.2016.02.002 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0165037815300735 | - |
| dc.rights | info:eu-repo/semantics/restrictedAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.subject | ANGIOGENIC FACTORS | - |
| dc.subject | GALECTIN-1 | - |
| dc.subject | HELLP | - |
| dc.subject | PREGNANCY | - |
| dc.subject | Inmunología | - |
| dc.subject | Medicina Básica | - |
| dc.subject | CIENCIAS MÉDICAS Y DE LA SALUD | - |
| dc.subject | Medicina Critica y de Emergencia | - |
| dc.subject | Medicina Clínica | - |
| dc.subject | CIENCIAS MÉDICAS Y DE LA SALUD | - |
| dc.title | Elevated systemic galectin-1 levels characterize HELLP syndrome. | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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