Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Dudiuk, Catiana Beatriz | - |
| dc.creator | Gamarra, Maria Soledad | - |
| dc.creator | Leonardelli, Florencia | - |
| dc.creator | Jimenez Ortigoza, Cristina | - |
| dc.creator | Vitale, Roxana Gabriela | - |
| dc.creator | Afeltra, Javier | - |
| dc.creator | Perlin, David S. | - |
| dc.creator | Garcia, Guillermo Manuel | - |
| dc.date | 2017-12-19T19:57:15Z | - |
| dc.date | 2017-12-19T19:57:15Z | - |
| dc.date | 2014-07 | - |
| dc.date | 2017-12-18T15:10:59Z | - |
| dc.date.accessioned | 2019-04-29T15:26:31Z | - |
| dc.date.available | 2019-04-29T15:26:31Z | - |
| dc.date.issued | 2014-07 | - |
| dc.identifier | Garcia, Guillermo Manuel; Perlin, David S.; Afeltra, Javier; Vitale, Roxana Gabriela; Jimenez Ortigoza, Cristina; Leonardelli, Florencia; et al.; Set of Classical PCRs for Detection of Mutations in Candida glabrata FKS Genes Linked with Echinocandin Resistance; American Society for Microbiology; Journal of Clinical Microbiology; 52; 7; 7-2014; 2609-2614 | - |
| dc.identifier | 0095-1137 | - |
| dc.identifier | http://hdl.handle.net/11336/31060 | - |
| dc.identifier | 1098-660X | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/294230 | - |
| dc.description | Clinical echinocandin resistance among Candida glabrata strains is increasing, especially in the United States. Antifungal susceptibility testing is considered mandatory to guide therapeutic decisions. However, these methodologies are not routinely performed in the hospital setting due to their complexity and the time needed to obtain reliable results. Echinocandin failure in C. glabrata is linked exclusively to Fks1p and Fks2p amino acid substitutions, and detection of such substitutions would serve as a surrogate marker to identify resistant isolates. In this work, we report an inexpensive, simple, and quick classical PCR set able to objectively detect the most common mechanisms of echinocandin resistance in C. glabrata within 4 h. The usefulness of this assay was assessed using a blind collection of 50 C. glabrata strains, including 16 FKS1 and/or FKS2 mutants. | - |
| dc.description | Fil: Dudiuk, Catiana Beatriz. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina | - |
| dc.description | Fil: Gamarra, Maria Soledad. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina | - |
| dc.description | Fil: Leonardelli, Florencia. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina | - |
| dc.description | Fil: Jimenez Ortigoza, Cristina. State University of New Jersey; Estados Unidos | - |
| dc.description | Fil: Vitale, Roxana Gabriela. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina | - |
| dc.description | Fil: Afeltra, Javier. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina | - |
| dc.description | Fil: Perlin, David S.. State University of New Jersey; Estados Unidos | - |
| dc.description | Fil: Garcia, Guillermo Manuel. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | American Society for Microbiology | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097693/ | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1128/JCM.01038-14 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/http://jcm.asm.org/content/52/7/2609.long | - |
| dc.rights | info:eu-repo/semantics/openAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.subject | CANDIDA | - |
| dc.subject | GLABRATA | - |
| dc.subject | RESISTENCIA | - |
| dc.subject | EQUINOCANDINAS | - |
| dc.subject | Otras Ciencias Biológicas | - |
| dc.subject | Ciencias Biológicas | - |
| dc.subject | CIENCIAS NATURALES Y EXACTAS | - |
| dc.title | Set of Classical PCRs for Detection of Mutations in Candida glabrata FKS Genes Linked with Echinocandin Resistance | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
Ficheros en este ítem:
No hay ficheros asociados a este ítem.