Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Smith, Matthew J. | - |
| dc.creator | Marshall, Christopher B. | - |
| dc.creator | Theillet, Francois Xavier | - |
| dc.creator | Binolfi, Andrés | - |
| dc.creator | Selenko, Philipp | - |
| dc.creator | Ikura, Mitsuhiko | - |
| dc.date | 2018-07-03T18:13:28Z | - |
| dc.date | 2018-07-03T18:13:28Z | - |
| dc.date | 2015-06 | - |
| dc.date | 2018-07-03T14:22:46Z | - |
| dc.date.accessioned | 2019-04-29T15:27:58Z | - |
| dc.date.available | 2019-04-29T15:27:58Z | - |
| dc.date.issued | 2018-07-03T18:13:28Z | - |
| dc.date.issued | 2018-07-03T18:13:28Z | - |
| dc.date.issued | 2015-06 | - |
| dc.date.issued | 2018-07-03T14:22:46Z | - |
| dc.identifier | Smith, Matthew J.; Marshall, Christopher B.; Theillet, Francois Xavier; Binolfi, Andrés; Selenko, Philipp; et al.; Real-time NMR monitoring of biological activities in complex physiological environments; Current Biology; Current Opinion In Structural Biology; 32; 6-2015; 39-47 | - |
| dc.identifier | 0959-440X | - |
| dc.identifier | http://hdl.handle.net/11336/51058 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/294659 | - |
| dc.description | Biological reactions occur in a highly organized spatiotemporal context and with kinetics that are modulated by multiple environmental factors. To integrate these variables in our experimental investigations of 'native' biological activities, we require quantitative tools for time-resolved in situ analyses in physiologically relevant settings. Here, we outline the use of high-resolution NMR spectroscopy to directly observe biological reactions in complex environments and in real-time. Specifically, we discuss how real-time NMR (RT-NMR) methods have delineated insights into metabolic processes, post-translational protein modifications, activities of cellular GTPases and their regulators, as well as of protein folding events. | - |
| dc.description | Fil: Smith, Matthew J.. Ontario Cancer Institute; Canadá | - |
| dc.description | Fil: Marshall, Christopher B.. Ontario Cancer Institute; Canadá | - |
| dc.description | Fil: Theillet, Francois Xavier. Leibniz Institute of Molecular Pharmacology; Alemania | - |
| dc.description | Fil: Binolfi, Andrés. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Leibniz Institute of Molecular Pharmacology; Alemania | - |
| dc.description | Fil: Selenko, Philipp. Leibniz Institute of Molecular Pharmacology; Alemania | - |
| dc.description | Fil: Ikura, Mitsuhiko. Ontario Cancer Institute; Canadá. University of Toronto; Canadá | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Current Biology | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1016/j.sbi.2015.02.003 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S0959440X15000123 | - |
| dc.rights | info:eu-repo/semantics/restrictedAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.subject | NMR | - |
| dc.subject | post-translational modifications | - |
| dc.subject | kinetics | - |
| dc.subject | Otras Ciencias Biológicas | - |
| dc.subject | Ciencias Biológicas | - |
| dc.subject | CIENCIAS NATURALES Y EXACTAS | - |
| dc.title | Real-time NMR monitoring of biological activities in complex physiological environments | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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