Registro completo de metadatos
Campo DC Valor Lengua/Idioma
dc.creatorMilanesi, Lorena Magdalena-
dc.creatorVasconsuelo, Andrea Anahi-
dc.creatorBoland, Ricardo Leopoldo-
dc.date2016-08-10T22:38:31Z-
dc.date2016-08-10T22:38:31Z-
dc.date2013-09-
dc.date2016-05-10T14:34:56Z-
dc.date.accessioned2019-04-29T15:29:28Z-
dc.date.available2019-04-29T15:29:28Z-
dc.date.issued2016-08-10T22:38:31Z-
dc.date.issued2016-08-10T22:38:31Z-
dc.date.issued2013-09-
dc.date.issued2016-05-10T14:34:56Z-
dc.identifierMilanesi, Lorena Magdalena; Vasconsuelo, Andrea Anahi; Boland, Ricardo Leopoldo; Actions of 17-estradiol and testosterone in the mitochondria and their implications in aging; Elsevier Ireland; Ageing Research Reviews; 12; 4; 9-2013; 907-917-
dc.identifier1568-1637-
dc.identifierhttp://hdl.handle.net/11336/7081-
dc.identifier.urihttp://rodna.bn.gov.ar:8080/jspui/handle/bnmm/295104-
dc.descriptionA decline in the mitochondrial functions and aging are two closely related processes. The presence of estrogen and androgen receptors and hormone-responsive elements in the mitochondria represents the starting point for the investigation of the effects of 17β-estradiol and testosterone on the mitochondrial functions and their relationships with aging. Both steroids trigger a complex molecular mechanism that involves crosstalk between the mitochondria, nucleus, and plasma membrane, and the cytoskeleton plays a key role in these interactions. The result of this signaling is mitochondrial protection. Therefore, the molecular components of the pathways activated by the sexual steroids could represent targets for anti-aging therapies. In this review, we discuss previous studies that describe the estrogen- and testosterone-dependent actions on the mitochondrial processes implicated in aging.-
dc.descriptionFil: Milanesi, Lorena Magdalena. Universidad Nacional del Sur; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnológico Bahia Blanca. Instituto de Ciencias Biologicas y Biomedicas del Sur; Argentina-
dc.descriptionFil: Vasconsuelo, Andrea Anahi. Universidad Nacional del Sur; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnológico Bahia Blanca. Instituto de Ciencias Biologicas y Biomedicas del Sur; Argentina-
dc.descriptionFil: Boland, Ricardo Leopoldo. Universidad Nacional del Sur; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnológico Bahia Blanca. Instituto de Ciencias Biologicas y Biomedicas del Sur; Argentina-
dc.formatapplication/pdf-
dc.formatapplication/pdf-
dc.languageeng-
dc.publisherElsevier Ireland-
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S1568163713000640-
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.arr.2013.09.001-
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.arr.2013.09.001-
dc.rightsinfo:eu-repo/semantics/restrictedAccess-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/-
dc.sourcereponame:CONICET Digital (CONICET)-
dc.sourceinstname:Consejo Nacional de Investigaciones Científicas y Técnicas-
dc.sourceinstacron:CONICET-
dc.subject17-BETA ESTRADIOL-
dc.subjectTESTOSTERONE-
dc.subjectAGING-
dc.subjectMITOCHONDRIA-
dc.subjectBioquímica y Biología Molecular-
dc.subjectMedicina Básica-
dc.subjectCIENCIAS MÉDICAS Y DE LA SALUD-
dc.titleActions of 17-estradiol and testosterone in the mitochondria and their implications in aging-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.typeinfo:ar-repo/semantics/articulo-
Aparece en las colecciones: CONICET

Ficheros en este ítem:
No hay ficheros asociados a este ítem.