Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Chimeo, Cindy | - |
| dc.creator | Fernandez Gimenez, Analia Veronica | - |
| dc.creator | Campanella, Michelangelo | - |
| dc.creator | Mendez Romero, Ofelia | - |
| dc.creator | Muhlia Almazan, Adriana | - |
| dc.date | 2018-06-29T19:23:02Z | - |
| dc.date | 2018-06-29T19:23:02Z | - |
| dc.date | 2015-10 | - |
| dc.date | 2018-06-29T13:08:00Z | - |
| dc.date.accessioned | 2019-04-29T15:31:02Z | - |
| dc.date.available | 2019-04-29T15:31:02Z | - |
| dc.date.issued | 2015-10 | - |
| dc.identifier | Chimeo, Cindy; Fernandez Gimenez, Analia Veronica; Campanella, Michelangelo; Mendez Romero, Ofelia; Muhlia Almazan, Adriana; The shrimp mitochondrial FoF1-ATPase inhibitory factor 1 (IF1); Springer/Plenum Publishers; Journal of Bioenergetics and Biomembranes; 47; 5; 10-2015; 383-393 | - |
| dc.identifier | 0145-479X | - |
| dc.identifier | http://hdl.handle.net/11336/50774 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/295569 | - |
| dc.description | The whiteleg shrimp species Litopenaeus vannamei is exposed to cyclic changes of the dissolved oxygen concentration of seawater and must neutralize the adverse effects of hypoxia by using ATP as energy source. In crustaceans, the mitochondrial FOF1-ATP synthase is pivotal to the homeostasis of ATP and function prevalently as a FOF1-ATPase. Hitherto, it is unknown whether these marine invertebrates are equipped with molecules able to control the FOF1-ATPase inhibiting the ATP consumption. In this study, we report two variants of the mitochondrial FOF1-ATPase Inhibitory Factor 1 (IF1) ubiquitously expressed across tissues of the Litopenaeus vannamei transcriptome: the IF1_Lv1 and the IF1_Lv2. The IF1_Lv1, with a full-length sequence of 550 bp, encodes a 104 aa long protein and its mRNA amounts are significantly affected by hypoxia and re-oxygenation. The IF1_Lv2, with a sequence of 654 bp, encodes instead for a protein of 85 aa. Both proteins share a 69 % homology and contain a conserved minimal inhibitory sequence (IATP domain) along with a G-rich region on their N-terminus typical of the invertebrate. In light of this characterization IF1 is here discussed as an adaptive mechanism evolved by this marine species to inhibit the FOF1-ATPase activity and avoid ATP dissipation to thrive in spite of the changes in oxygen tension. | - |
| dc.description | Fil: Chimeo, Cindy. Centro de Investigacion en Alimentacion y Desarrollo; México | - |
| dc.description | Fil: Fernandez Gimenez, Analia Veronica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Marinas y Costeras. Universidad Nacional de Mar del Plata. Facultad de Ciencia Exactas y Naturales. Instituto de Investigaciones Marinas y Costeras; Argentina | - |
| dc.description | Fil: Campanella, Michelangelo. University of London; Reino Unido. University College London; Estados Unidos | - |
| dc.description | Fil: Mendez Romero, Ofelia. Centro de Investigacion en Alimentacion y Desarrollo; México | - |
| dc.description | Fil: Muhlia Almazan, Adriana. Centro de Investigacion en Alimentacion y Desarrollo; México | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Springer/Plenum Publishers | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1007/s10863-015-9621-0 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs10863-015-9621-0 | - |
| dc.rights | info:eu-repo/semantics/restrictedAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.subject | HYPOXIA | - |
| dc.subject | IF1, FOF1-ATPASE | - |
| dc.subject | INHIBITOR | - |
| dc.subject | SHRIMP | - |
| dc.subject | TRANSCRIPTIONAL REGULATION | - |
| dc.subject | Otras Ciencias Biológicas | - |
| dc.subject | Ciencias Biológicas | - |
| dc.subject | CIENCIAS NATURALES Y EXACTAS | - |
| dc.title | The shrimp mitochondrial FoF1-ATPase inhibitory factor 1 (IF1) | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
Ficheros en este ítem:
No hay ficheros asociados a este ítem.