Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Antunica Noguerol, María de Las Nieves | - |
| dc.creator | Aprile García, Fernando | - |
| dc.creator | Budziñski, Maia Ludmila | - |
| dc.creator | Proto Cassina, Luciano Matias | - |
| dc.creator | Liberman, Ana Clara | - |
| dc.creator | Arzt, Eduardo Simon | - |
| dc.date | 2017-12-26T20:09:06Z | - |
| dc.date | 2017-12-26T20:09:06Z | - |
| dc.date | 2014-07 | - |
| dc.date | 2017-12-11T15:03:20Z | - |
| dc.date.accessioned | 2019-04-29T15:31:25Z | - |
| dc.date.available | 2019-04-29T15:31:25Z | - |
| dc.date.issued | 2014-07 | - |
| dc.identifier | Proto Cassina, Luciano Matias; Aprile García, Fernando; Antunica Noguerol, María de Las Nieves; Arzt, Eduardo Simon; Liberman, Ana Clara; Budziñski, Maia Ludmila; et al.; The Interplay between the Glucocorticoid Receptor Activity and post-Translational Modifications in the Immune and Neuroendocrine Systems; IOS Press; Advances in Neuroimmune Biology; 5; 1; 7-2014; 19-32 | - |
| dc.identifier | 1878-948X | - |
| dc.identifier | http://hdl.handle.net/11336/31597 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/295719 | - |
| dc.description | Glucocorticoids (GCs), the most downstream effectors of the hypothalamic-pituitary-adrenal (HPA) axis, are key mediators in the interaction between immune and neuroendocrine systems. They exert their biological actions mainly through binding to their intracellular receptor, the glucocorticoid receptor (GR), which in turn influences gene expression by interacting with transcription factors and/or coregulators. GR abnormal function has been extensively associated to stress-related disorders, inflammatory and autoimmune diseases. Therefore, modulating GR activity is critical to overcome pathological conditions. The final outcome of GCs actions in the immune and neuroendocrine systems is regulated at multiple levels, including post-translational modifications (PTMs) of GR as well as of protein complexes involved in GR signaling. Understanding the influence of PTMs on the molecular mechanisms involved in GR signaling is thus of utmost importance in the search for therapeutic strategies aimed at modulating GR responses under pathophysiological circumstances, and to understand the neuroimmune circuits. | - |
| dc.description | Fil: Antunica Noguerol, María de Las Nieves. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigación en Biomedicina de Buenos Aires - Instituto Partner de la Sociedad Max Planck; Argentina | - |
| dc.description | Fil: Aprile García, Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigación en Biomedicina de Buenos Aires - Instituto Partner de la Sociedad Max Planck; Argentina | - |
| dc.description | Fil: Budziñski, Maia Ludmila. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigación en Biomedicina de Buenos Aires - Instituto Partner de la Sociedad Max Planck; Argentina | - |
| dc.description | Fil: Proto Cassina, Luciano Matias. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigación en Biomedicina de Buenos Aires - Instituto Partner de la Sociedad Max Planck; Argentina | - |
| dc.description | Fil: Liberman, Ana Clara. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigación en Biomedicina de Buenos Aires - Instituto Partner de la Sociedad Max Planck; Argentina | - |
| dc.description | Fil: Arzt, Eduardo Simon. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigación en Biomedicina de Buenos Aires - Instituto Partner de la Sociedad Max Planck; Argentina | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | IOS Press | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/https://content.iospress.com/articles/advances-in-neuroimmune-biology/nib140083 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3233/NIB-140083 | - |
| dc.rights | info:eu-repo/semantics/restrictedAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.subject | Glucocorticoid receptor | - |
| dc.subject | post-translational modifications | - |
| dc.subject | NEUROIMMUNOLOGY | - |
| dc.subject | transcription regulation | - |
| dc.subject | Otras Ciencias Biológicas | - |
| dc.subject | Ciencias Biológicas | - |
| dc.subject | CIENCIAS NATURALES Y EXACTAS | - |
| dc.title | The Interplay between the Glucocorticoid Receptor Activity and post-Translational Modifications in the Immune and Neuroendocrine Systems | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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