Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Goszczynski, Daniel Estanislao | - |
| dc.creator | Ripoli, María Verónica | - |
| dc.creator | Takeshima, S.N. | - |
| dc.creator | Baltian, Laura Rosana | - |
| dc.creator | Aida, Y. | - |
| dc.creator | Giovambattista, Guillermo | - |
| dc.date | 2017-09-21T20:06:40Z | - |
| dc.date | 2017-09-21T20:06:40Z | - |
| dc.date | 2014-02-06 | - |
| dc.date | 2017-09-18T14:32:58Z | - |
| dc.date.accessioned | 2019-04-29T15:32:31Z | - |
| dc.date.available | 2019-04-29T15:32:31Z | - |
| dc.date.issued | 2017-09-21T20:06:40Z | - |
| dc.date.issued | 2017-09-21T20:06:40Z | - |
| dc.date.issued | 2014-02-06 | - |
| dc.date.issued | 2017-09-18T14:32:58Z | - |
| dc.identifier | Goszczynski, Daniel Estanislao; Ripoli, María Verónica; Takeshima, S.N.; Baltian, Laura Rosana; Aida, Y.; et al.; Haplotype determination of the upstream regulatory region and the second exon of the BoLA-DRB3 gene in Holstein cattle; Wiley Blackwell Publishing, Inc; Tissue Antigens; 83; 3; 6-2-2014; 180-183 | - |
| dc.identifier | 0001-2815 | - |
| dc.identifier | http://hdl.handle.net/11336/24845 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/296110 | - |
| dc.description | Polymorphisms of the BoLA-DRB3 gene are located primarily in the second exon [antigen binding site (ABS)] and, to a lesser extent, in the upstream regulatory region (URR). It can be hypothesised that exon 2 and the URR are under different types of natural selection. The aim of this work was to determine the URR-exon 2 haplotypes; 34 Holstein samples were genotyped by direct sequencing. A total of 7 URR alleles and 23 exon 2 alleles were detected, and 3 of the URR alleles were novel. Our results may suggest that no relationship exists between the URR and exon 2 of the BoLA-DRB3 gene (linkage disequilibrium P value > 0.05), most likely due to recombination over time. Our results also suggest that both regions of class II genes may be included in the development of new genotyping methods based on nextgeneration DNA sequencing technologies. | - |
| dc.description | Fil: Goszczynski, Daniel Estanislao. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina | - |
| dc.description | Fil: Ripoli, María Verónica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina | - |
| dc.description | Fil: Takeshima, S.N.. Viral Infectious Diseases Unit; Japón | - |
| dc.description | Fil: Baltian, Laura Rosana. Universidad Nacional de La Pampa; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina | - |
| dc.description | Fil: Aida, Y.. Viral Infectious Diseases Unit; Japón | - |
| dc.description | Fil: Giovambattista, Guillermo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Wiley Blackwell Publishing, Inc | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1111/tan.12293 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1111/tan.12293/abstract | - |
| dc.rights | info:eu-repo/semantics/restrictedAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.subject | BoLA-DRB3 | - |
| dc.subject | linkage disequilibrium | - |
| dc.subject | polymorphism | - |
| dc.subject | selection | - |
| dc.title | Haplotype determination of the upstream regulatory region and the second exon of the BoLA-DRB3 gene in Holstein cattle | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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