Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.provenance | CONICET | - |
| dc.creator | Dilernia, Darío Alberto | - |
| dc.creator | Jones, Leandro Roberto | - |
| dc.creator | Pando, María de los Ángeles | - |
| dc.creator | Rabinovich, Roberto Daniel | - |
| dc.creator | Damilano, Gabriel Dario | - |
| dc.creator | Turk, Gabriela Julia Ana | - |
| dc.creator | Rubio, Andrea | - |
| dc.creator | Pampuro, Sandra Esther | - |
| dc.creator | Gómez Carrillo, Manuel | - |
| dc.creator | Salomon, Horacio Eduardo | - |
| dc.date | 2019-01-03T15:17:10Z | - |
| dc.date | 2019-01-03T15:17:10Z | - |
| dc.date | 2011-05 | - |
| dc.date | 2019-01-02T19:54:50Z | - |
| dc.date.accessioned | 2019-04-29T15:32:54Z | - |
| dc.date.available | 2019-04-29T15:32:54Z | - |
| dc.date.issued | 2019-01-03T15:17:10Z | - |
| dc.date.issued | 2019-01-03T15:17:10Z | - |
| dc.date.issued | 2011-05 | - |
| dc.date.issued | 2019-01-02T19:54:50Z | - |
| dc.identifier | Dilernia, Darío Alberto; Jones, Leandro Roberto; Pando, María de los Ángeles; Rabinovich, Roberto Daniel; Damilano, Gabriel Dario; et al.; Analysis of HIV type 1 BF recombinant sequences from south america dates the origin of CRF12-BF to a recombination event in the 1970s; Mary Ann Liebert; Aids Research and Human Retroviruses; 27; 5; 5-2011; 569-578 | - |
| dc.identifier | 0889-2229 | - |
| dc.identifier | http://hdl.handle.net/11336/67287 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/296268 | - |
| dc.description | HIV-1 epidemics in South America are believed to have originated in part from the subtype B epidemic initiated in the Caribbean/North America region. However, circulation of BF recombinants in similar proportions was extensively reported. Information currently shows that many BF recombinants share a recombination structure similar to that found in the CRF12-BF. In the present study, analyzing a set of 405 HIV sequences, we identified the most likely origin of the BF epidemic in an early event of recombination. We found that the subtype B epidemics in South America analyzed in the present study were initiated by a founder event that occurred in the early 1970s, a few years after the introduction of these strains in the Americas. Regarding the F/BF recombinant epidemics, by analyzing a subtype F genomic segment within the viral gene gag present in the majority of the BF recombinants, we found evidence of a geographic divergence very soon after the introduction of subtype F strains in South America. Moreover, through analysis of a subtype B segment present in all the CRF12-BF-like recombination structure, we estimated the circulation of the subtype B strain that gave rise to that recombinant structure around the same time period estimated for the introduction of subtype F strains. The HIV epidemics in South America were initiated in part through a founder event driven by subtype B strains coming from the previously established epidemic in the north of the continent. A second introduction driven by subtype F strains is likely to have encountered the incipient subtype B epidemic that soon after their arrival recombined with them, originating the BF epidemic in the region. These results may explain why in South America the majority of F sequences are found as BF recombinants. © Copyright 2011, Mary Ann Liebert, Inc. | - |
| dc.description | Fil: Dilernia, Darío Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Microbiología; Argentina | - |
| dc.description | Fil: Jones, Leandro Roberto. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Estación de fotobiología ‘‘Playa Unión’’; Argentina | - |
| dc.description | Fil: Pando, María de los Ángeles. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Microbiología; Argentina | - |
| dc.description | Fil: Rabinovich, Roberto Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Microbiología; Argentina | - |
| dc.description | Fil: Damilano, Gabriel Dario. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Microbiología; Argentina | - |
| dc.description | Fil: Turk, Gabriela Julia Ana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Microbiología; Argentina | - |
| dc.description | Fil: Rubio, Andrea. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Microbiología; Argentina | - |
| dc.description | Fil: Pampuro, Sandra Esther. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Microbiología; Argentina | - |
| dc.description | Fil: Gómez Carrillo, Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Microbiología; Argentina | - |
| dc.description | Fil: Salomon, Horacio Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Microbiología; Argentina | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Mary Ann Liebert | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1089/aid.2010.0118 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/https://www.liebertpub.com/doi/10.1089/aid.2010.0118 | - |
| dc.rights | info:eu-repo/semantics/openAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.source.uri | http://hdl.handle.net/11336/67287 | - |
| dc.subject | no corresponde | - |
| dc.subject | Otras Ciencias Biológicas | - |
| dc.subject | Ciencias Biológicas | - |
| dc.subject | CIENCIAS NATURALES Y EXACTAS | - |
| dc.title | Analysis of HIV type 1 BF recombinant sequences from south america dates the origin of CRF12-BF to a recombination event in the 1970s | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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