Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.provenance | CONICET | - |
| dc.creator | Gimeno, Marina | - |
| dc.creator | Pinczowski, Pedro | - |
| dc.creator | Pérez, Marta | - |
| dc.creator | Giorello, Antonella | - |
| dc.creator | Martinez, Miguel Angel | - |
| dc.creator | Santamaría, Jesús | - |
| dc.creator | Arruebo, Manuel | - |
| dc.creator | Luján, Lluis | - |
| dc.date | 2018-02-16T19:13:38Z | - |
| dc.date | 2018-02-16T19:13:38Z | - |
| dc.date | 2015-10 | - |
| dc.date | 2018-01-18T14:39:46Z | - |
| dc.date.accessioned | 2019-04-29T15:33:43Z | - |
| dc.date.available | 2019-04-29T15:33:43Z | - |
| dc.date.issued | 2015-10 | - |
| dc.identifier | Gimeno, Marina; Pinczowski, Pedro; Pérez, Marta; Giorello, Antonella; Martinez, Miguel Angel; et al.; A controlled antibiotic release system to prevent orthopedic-implant associated infections: An in vitro study; Elsevier; European Journal Of Pharmaceutics And Biopharmaceutics; 96; 10-2015; 264-271 | - |
| dc.identifier | 0939-6411 | - |
| dc.identifier | http://hdl.handle.net/11336/36650 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/296577 | - |
| dc.description | A new device for local delivery of antibiotics is presented, with potential use as a drug-eluting fixation pin for orthopedic applications. The implant consists of a stainless steel hollow tubular reservoir packed with the desired antibiotic. Release takes place through several orifices previously drilled in the reservoir wall, a process that does not compromise the mechanical properties required for the implant. Depending on the antibiotic chosen and the number of orifices, the release profile can be tailored from a rapid release of the load (ca. 20 h) to a combination of rapid initial release and slower, sustained release for a longer period of time (ca. 200 h). An excellent bactericidal action is obtained, with 4-log reductions achieved in as little as 2 h, and total bacterial eradication in 8 h using 6-pinholed implants filled with cefazolin. | - |
| dc.description | Fil: Gimeno, Marina. Universidad de Zaragoza; España | - |
| dc.description | Fil: Pinczowski, Pedro. Universidad de Zaragoza; España | - |
| dc.description | Fil: Pérez, Marta. Universidad de Zaragoza; España | - |
| dc.description | Fil: Giorello, Antonella. Universidad de Zaragoza. Instituto de Nanociencia de Aragón; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica ; Argentina | - |
| dc.description | Fil: Martinez, Miguel Angel. Universidad de Zaragoza; España. Networking Research Center on Bioengineering, Biomaterials and Nanomedicine, CIBER-BBN; España | - |
| dc.description | Fil: Santamaría, Jesús. Universidad de Zaragoza; España. Networking Research Center on Bioengineering, Biomaterials and Nanomedicine, CIBER-BBN; España | - |
| dc.description | Fil: Arruebo, Manuel. Universidad de Zaragoza; España. Networking Research Center on Bioengineering, Biomaterials and Nanomedicine, CIBER-BBN; España | - |
| dc.description | Fil: Luján, Lluis. Universidad de Zaragoza; España | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Elsevier | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0939641115003392 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.ejpb.2015.08.007 | - |
| dc.rights | info:eu-repo/semantics/restrictedAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.source.uri | http://hdl.handle.net/11336/36650 | - |
| dc.subject | ANTIBIOTIC | - |
| dc.subject | CONTROLLED RELEASE | - |
| dc.subject | HOLLOW STEEL IMPLANT | - |
| dc.subject | MEDICAL DEVICE | - |
| dc.subject | ORTHOPEDIC SURGERY | - |
| dc.subject | STAPHYLOCOCCUS AUREUS | - |
| dc.subject | Inmunología | - |
| dc.subject | Medicina Básica | - |
| dc.subject | CIENCIAS MÉDICAS Y DE LA SALUD | - |
| dc.title | A controlled antibiotic release system to prevent orthopedic-implant associated infections: An in vitro study | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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