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dc.provenanceCONICET-
dc.creatorMartínez Cortés, Gabriela-
dc.creatorSalazar Flores, Joel-
dc.creatorHaro Guerrero, Javier-
dc.creatorRubi Castellanos, Rodrigo-
dc.creatorVelarde Félix, Jesus S.-
dc.creatorMuñoz Valle, Jose F.-
dc.creatorLópez Casamichana, Mavil-
dc.creatorCarrillo Tapia, Eduardo-
dc.creatorCasenco Avila, Luis M.-
dc.creatorBravi, Claudio Marcelo-
dc.creatorLópez Armenta, Mauro-
dc.creatorRangel Villalobos, Hector-
dc.date2017-09-11T19:01:18Z-
dc.date2017-09-11T19:01:18Z-
dc.date2013-06-11-
dc.date2017-09-06T17:15:56Z-
dc.date.accessioned2019-04-29T15:36:11Z-
dc.date.available2019-04-29T15:36:11Z-
dc.date.issued2013-06-11-
dc.identifierMartínez Cortés, Gabriela; Salazar Flores, Joel; Haro Guerrero, Javier; Rubi Castellanos, Rodrigo; Velarde Félix, Jesus S.; et al.; Maternal admixture and population structure in Mexican-mestizos based on mtDNA haplogroups; Wiley-liss, Div John Wiley & Sons Inc; American Journal Of Physical Anthropology; 151; 4; 11-6-2013; 526-537-
dc.identifier0002-9483-
dc.identifierhttp://hdl.handle.net/11336/23928-
dc.identifierCONICET Digital-
dc.identifierCONICET-
dc.identifier.urihttp://rodna.bn.gov.ar:8080/jspui/handle/bnmm/297522-
dc.descriptionThe maternal ancestry (mtDNA) has important applications in different research fields, such as evolution, epidemiology, identification, and human population history. This is particularly interesting in Mestizos, which constitute the main population in Mexico (∼93%) resulting from post-Columbian admixture between Spaniards, Amerindians, and African slaves, principally. Consequently, we conducted minisequencing analysis (SNaPshot) of 11 mitochondrial single-nucleotide polymorphisms in 742 Mestizos of 10 populations from different regions in Mexico. The predominant maternal ancestry was Native American (92.9%), including Haplogroups A, B, C, and D (47, 23.7, 15.9, and 6.2%, respectively). Conversely, European and African ancestries were less frequent (5.3 and 1.9%, respectively). The main characteristics of the maternal lineages observed in Mexican–Mestizos comprised the following: 1) contrasting geographic gradient of Haplogroups A and C; 2) increase of European lineages toward the Northwest; 3) low or absent, but homogeneous, African ancestry throughout the Mexican territory; 4) maternal lineages in Mestizos roughly represent the genetic makeup of the surrounding Amerindian groups, particularly toward the Southeast, but not in the North and West; 5) continuity over time of the geographic distribution of Amerindian lineages in Mayas; and 6) low but significant maternal population structure (FST = 2.8%; P = 0.0000). The average ancestry obtained from uniparental systems (mtDNA and Y-chromosome) in Mexican–Mestizos was correlated with previous ancestry estimates based on autosomal systems (genome-wide single-nucleotide polymorphisms and short tandem repeats). Finally, the comparison of paternal and maternal lineages provided additional information concerning the gender bias admixture, mating patterns, and population structure in Mestizos throughout the Mexican territory. Am J Phys Anthropol.-
dc.descriptionFil: Martínez Cortés, Gabriela. Universidad de Guadalajara; México-
dc.descriptionFil: Salazar Flores, Joel. Universidad de Guadalajara; México-
dc.descriptionFil: Haro Guerrero, Javier. Universidad de Guadalajara; México-
dc.descriptionFil: Rubi Castellanos, Rodrigo. Universidad de Guadalajara; México-
dc.descriptionFil: Velarde Félix, Jesus S.. Universidad Autonoma de Sinaloa; México-
dc.descriptionFil: Muñoz Valle, Jose F.. Universidad de Guadalajara; México-
dc.descriptionFil: López Casamichana, Mavil. Universidad Nacional Autónoma de México; México-
dc.descriptionFil: Carrillo Tapia, Eduardo. Universidad Nacional Autónoma de México; México-
dc.descriptionFil: Casenco Avila, Luis M.. Hospital Regional de Alta Especialidad. Laboratorio de Investigación; México-
dc.descriptionFil: Bravi, Claudio Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina-
dc.descriptionFil: López Armenta, Mauro. Universidad Nacional Autónoma de México; México-
dc.descriptionFil: Rangel Villalobos, Hector. Universidad de Guadalajara; México-
dc.formatapplication/pdf-
dc.formatapplication/pdf-
dc.languageeng-
dc.publisherWiley-liss, Div John Wiley & Sons Inc-
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/ajpa.22293/abstract-
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1002/ajpa.22293-
dc.rightsinfo:eu-repo/semantics/restrictedAccess-
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/-
dc.sourcereponame:CONICET Digital (CONICET)-
dc.sourceinstname:Consejo Nacional de Investigaciones Científicas y Técnicas-
dc.sourceinstacron:CONICET-
dc.source.urihttp://hdl.handle.net/11336/23928-
dc.subjectMTDNA ANCESTRY-
dc.subjectMATERNAL ADMIXTURE-
dc.subjectMEXICAN-MESTIZO-
dc.subjectmtSNPs-
dc.subjectY-SNPs-
dc.subjectBioquímica y Biología Molecular-
dc.subjectCiencias Biológicas-
dc.subjectCIENCIAS NATURALES Y EXACTAS-
dc.titleMaternal admixture and population structure in Mexican-mestizos based on mtDNA haplogroups-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.typeinfo:ar-repo/semantics/articulo-
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