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Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.provenance | CONICET | - |
dc.creator | Pietri, Thomas | - |
dc.creator | Romano, Sebastián A. | - |
dc.creator | Pérez Schuster, Verónica | - |
dc.creator | Boulanger Weill, Jonathan | - |
dc.creator | Candat, Virginie | - |
dc.creator | Sumbre, Germán | - |
dc.date | 2018-11-13T21:05:30Z | - |
dc.date | 2018-11-13T21:05:30Z | - |
dc.date | 2017-05 | - |
dc.date | 2018-10-23T18:08:54Z | - |
dc.date.accessioned | 2019-04-29T15:37:57Z | - |
dc.date.available | 2019-04-29T15:37:57Z | - |
dc.date.issued | 2017-05 | - |
dc.identifier | Pietri, Thomas; Romano, Sebastián A.; Pérez Schuster, Verónica; Boulanger Weill, Jonathan; Candat, Virginie; et al.; The Emergence of the Spatial Structure of Tectal Spontaneous Activity Is Independent of Visual Inputs; Elsevier; Cell Reports; 19; 5; 5-2017; 939-948 | - |
dc.identifier | 2211-1247 | - |
dc.identifier | http://hdl.handle.net/11336/64413 | - |
dc.identifier | CONICET Digital | - |
dc.identifier | CONICET | - |
dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/298123 | - |
dc.description | The brain is spontaneously active, even in the absence of sensory stimulation. The functionally mature zebrafish optic tectum shows spontaneous activity patterns reflecting a functional connectivity adapted for the circuit's functional role and predictive of behavior. However, neither the emergence of these patterns during development nor the role of retinal inputs in their maturation has been characterized. Using two-photon calcium imaging, we analyzed spontaneous activity in intact and enucleated zebrafish larvae throughout tectum development. At the onset of retinotectal connections, intact larvae showed major changes in the spatiotemporal structure of spontaneous activity. Although the absence of retinal inputs had a significant impact on the development of the temporal structure, the tectum was still capable of developing a spatial structure associated with the circuit's functional roles and predictive of behavior. We conclude that neither visual experience nor intrinsic retinal activity is essential for the emergence of a spatially structured functional circuit. | - |
dc.description | Fil: Pietri, Thomas. Centre National de la Recherche Scientifique. Ecole Normale Supérieure; Francia. New Jersey Institute of Technology; Estados Unidos | - |
dc.description | Fil: Romano, Sebastián A.. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigación en Biomedicina de Buenos Aires - Instituto Partner de la Sociedad Max Planck; Argentina. Centre National de la Recherche Scientifique. Ecole Normale Supérieure; Francia | - |
dc.description | Fil: Pérez Schuster, Verónica. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina. Centre National de la Recherche Scientifique. Ecole Normale Supérieure; Francia | - |
dc.description | Fil: Boulanger Weill, Jonathan. Centre National de la Recherche Scientifique. Ecole Normale Supérieure; Francia | - |
dc.description | Fil: Candat, Virginie. Centre National de la Recherche Scientifique. Ecole Normale Supérieure; Francia | - |
dc.description | Fil: Sumbre, Germán. Centre National de la Recherche Scientifique. Ecole Normale Supérieure; Francia | - |
dc.format | application/pdf | - |
dc.format | application/zip | - |
dc.format | application/pdf | - |
dc.language | eng | - |
dc.publisher | Elsevier | - |
dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.celrep.2017.04.015 | - |
dc.relation | info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S2211124717304904 | - |
dc.rights | info:eu-repo/semantics/openAccess | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.5/ar/ | - |
dc.source | reponame:CONICET Digital (CONICET) | - |
dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
dc.source | instacron:CONICET | - |
dc.source.uri | http://hdl.handle.net/11336/64413 | - |
dc.subject | BEHAVIOR | - |
dc.subject | DEVELOPMENT OF SPONTANEOUS ACTIVITY | - |
dc.subject | NEURONAL CIRCUIT DYNAMICS | - |
dc.subject | OPTIC TECTUM | - |
dc.subject | RETINAL INPUT | - |
dc.subject | VISUAL SYSTEM | - |
dc.subject | ZEBRAFISH | - |
dc.subject | Otras Ciencias Biológicas | - |
dc.subject | Ciencias Biológicas | - |
dc.subject | CIENCIAS NATURALES Y EXACTAS | - |
dc.title | The Emergence of the Spatial Structure of Tectal Spontaneous Activity Is Independent of Visual Inputs | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.type | info:ar-repo/semantics/articulo | - |
Aparece en las colecciones: | CONICET |
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