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dc.creatorVera Candioti, Josefina-
dc.creatorSoloneski, Sonia Maria Elsa-
dc.creatorLarramendy, Marcelo Luis-
dc.date2017-06-29T19:10:40Z-
dc.date2017-06-29T19:10:40Z-
dc.date2015-03-
dc.date2017-06-08T19:47:08Z-
dc.date.accessioned2019-04-29T15:40:10Z-
dc.date.available2019-04-29T15:40:10Z-
dc.date.issued2017-06-29T19:10:40Z-
dc.date.issued2017-06-29T19:10:40Z-
dc.date.issued2015-03-
dc.date.issued2017-06-08T19:47:08Z-
dc.identifierVera Candioti, Josefina; Soloneski, Sonia Maria Elsa; Larramendy, Marcelo Luis; Pirimicarb-based formulation-induced genotoxicity and cytotoxicity on the fresh water fish Cnesterodon decemmaculatus (Jenyns, 1842) (Pisces, Poeciliidae); Sage Publications Ltd; Toxicology And Industrial Health; 31; 11; 3-2015; 1051-1060-
dc.identifier0748-2337-
dc.identifierhttp://hdl.handle.net/11336/19171-
dc.identifierCONICET Digital-
dc.identifierCONICET-
dc.identifier.urihttp://rodna.bn.gov.ar:8080/jspui/handle/bnmm/299044-
dc.descriptionWe analyzed the aspects of lethality, genotoxicity, and cytotoxicity in the ten spotted live-bearer exposed under laboratory conditions to the pirimicarb-based formulation Patton Flow1 (50% active ingredient (a.i.)). Acute effects were evaluated using different end points for lethality, genotoxicity, and cytotoxicity. Median lethal concentration (LC50) estimation was employed as a bioassay for lethality, whereas micronucleus (MN) induction and alterations in erythrocyte/erythroblast frequency were used as end points for genotoxicity and cytotoxicity, respectively. Results demonstrated an LC5096h value of 88 mg/L. Patton Flow1 increased the MN frequency in fish erythrocytes after 48 h of exposure at a concentration of 66 mg/L, whereas a concentration range of 22?66 mg/L was able to exert the same genotoxic effect at 96 h of treatment. Furthermore, cytotoxicity was also observed by alterations in erythrocyte/erythroblast frequencies within the concentration range of 22? 66 mg/L, regardless of the exposure time. Our current observations provide evidence that Patton Flow1 (50% a.i.) should be considered a clear lethal, cytotoxic, and genotoxic agent on Cnesterodon decemmaculatus. Thus, repeated applications of this carbamic insecticide can enter the aquatic environment and exert deleterious effects on aquatic organisms other than the evaluated species C. decemmaculatus.-
dc.descriptionFil: Vera Candioti, Josefina. Universidad Nacional de la Plata. Facultad de Cs.naturales y Museo. Laboratorio de Citogenetica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina-
dc.descriptionFil: Soloneski, Sonia Maria Elsa. Universidad Nacional de la Plata. Facultad de Cs.naturales y Museo. Laboratorio de Citogenetica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina-
dc.descriptionFil: Larramendy, Marcelo Luis. Universidad Nacional de la Plata. Facultad de Cs.naturales y Museo. Laboratorio de Citogenetica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina-
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dc.languageeng-
dc.publisherSage Publications Ltd-
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1177/0748233713486958-
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://journals.sagepub.com/doi/10.1177/0748233713486958-
dc.rightsinfo:eu-repo/semantics/restrictedAccess-
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/-
dc.sourcereponame:CONICET Digital (CONICET)-
dc.sourceinstname:Consejo Nacional de Investigaciones Científicas y Técnicas-
dc.sourceinstacron:CONICET-
dc.subjectPatton Flow-
dc.subjecterythrocyte-
dc.subjecterythroblast ratio-
dc.subjectmicronucleus-
dc.subjectmortality-
dc.subjectpoeciliidae-
dc.subjectBiología Celular, Microbiología-
dc.subjectCiencias Biológicas-
dc.subjectCIENCIAS NATURALES Y EXACTAS-
dc.titlePirimicarb-based formulation-induced genotoxicity and cytotoxicity on the fresh water fish Cnesterodon decemmaculatus (Jenyns, 1842) (Pisces, Poeciliidae)-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.typeinfo:ar-repo/semantics/articulo-
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