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dc.creatorPorrás, Analía I.-
dc.creatorYadón, Zaida E.-
dc.creatorAltcheh, Jaime Marcelo-
dc.creatorBritto, Constança-
dc.creatorChaves, Gabriela C.-
dc.creatorFlevaud, Laurence-
dc.creatorMartins Filho, Olindo Assis-
dc.creatorRibeiro, Isabela-
dc.creatorSchijman, Alejandro Gabriel-
dc.creatorShikanai-Yasuda, Maria Aparecida-
dc.creatorSosa-Estani, Sergio Alejandro-
dc.creatorStobbaerts, Eric-
dc.creatorZicker, Fabio-
dc.date2018-04-10T20:23:14Z-
dc.date2018-04-10T20:23:14Z-
dc.date2015-06-
dc.date2018-04-10T17:53:41Z-
dc.date.accessioned2019-04-29T15:40:19Z-
dc.date.available2019-04-29T15:40:19Z-
dc.date.issued2018-04-10T20:23:14Z-
dc.date.issued2018-04-10T20:23:14Z-
dc.date.issued2015-06-
dc.date.issued2018-04-10T17:53:41Z-
dc.identifierPorrás, Analía I.; Yadón, Zaida E.; Altcheh, Jaime Marcelo; Britto, Constança; Chaves, Gabriela C.; et al.; Target Product Profile (TPP) for Chagas Disease Point-of-Care Diagnosis and Assessment of Response to Treatment; Public Library of Science; Neglected Tropical Diseases; 9; 6; 6-2015; 1-8;-
dc.identifier1935-2735-
dc.identifierhttp://hdl.handle.net/11336/41602-
dc.identifierCONICET Digital-
dc.identifierCONICET-
dc.identifier.urihttp://rodna.bn.gov.ar:8080/jspui/handle/bnmm/299101-
dc.descriptionChagas disease, or American trypanosomiasis, affects 8 million people, largely in Latin America, where it is endemic in all countries. With an overall estimate of 65 million people at risk of contracting the disease, 28,000 new cases every year, and 12,000 deaths annually, Chagas disease is the most important parasitic disease in the Americas [1]. In addition, nonendemic countries such as the United States [2,3], Canada [4], Germany [5], Italy [6], Spain [7,8], Switzerland [9,10], and France [11] have experienced the occurrence of Trypanosoma cruzi?infected and Chagas disease cases; the majority of these cases are among immigrants coming from endemic Latin American countries [12]. Like other neglected tropical diseases (NTDs), Chagas disease affects mostly poor populations with limited access to health services. Vector transmission is associated with poor housing in periurban and rural areas. After infection, the disease is characterized by an acute phase, usually asymptomatic, which evolves in 20%?30% of the patients to a chronic disabling cardiac and/or digestive clinical form. The remaining infected individuals evolve to a chronic asymptomatic but infective clinical phase [13]. Reactivation of chronic Chagas disease may occur associated with comorbidities such as HIV/AIDS, organ transplants, or immunosuppressive therapy.-
dc.descriptionFil: Porrás, Analía I.. Organización Panamericana de La Salud; Estados Unidos-
dc.descriptionFil: Yadón, Zaida E.. Organización Panamericana de La Salud; Estados Unidos-
dc.descriptionFil: Altcheh, Jaime Marcelo. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina-
dc.descriptionFil: Britto, Constança. Instituto Oswaldo Cruz; Brasil-
dc.descriptionFil: Chaves, Gabriela C.. Fundación Oswaldo Cruz; Brasil-
dc.descriptionFil: Flevaud, Laurence. Médicos Sin Fronteras. Centro Operacional Barcelona-Atenas; España-
dc.descriptionFil: Martins Filho, Olindo Assis. Instituto Oswaldo Cruz; Brasil-
dc.descriptionFil: Ribeiro, Isabela. Drugs for Neglected Diseases initiative; Brasil-
dc.descriptionFil: Schijman, Alejandro Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentina-
dc.descriptionFil: Shikanai-Yasuda, Maria Aparecida. Universidade de Sao Paulo; Brasil-
dc.descriptionFil: Sosa-Estani, Sergio Alejandro. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud “Dr. C. G. Malbrán”; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina-
dc.descriptionFil: Stobbaerts, Eric. Drugs for Neglected Diseases initiative; Brasil-
dc.descriptionFil: Zicker, Fabio. Fundación Oswaldo Cruz; Brasil-
dc.formatapplication/pdf-
dc.formatapplication/pdf-
dc.formatapplication/pdf-
dc.formatapplication/pdf-
dc.languageeng-
dc.publisherPublic Library of Science-
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456144/-
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1371%2Fjournal.pntd.0003697-
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0003697-
dc.rightsinfo:eu-repo/semantics/openAccess-
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/-
dc.sourcereponame:CONICET Digital (CONICET)-
dc.sourceinstname:Consejo Nacional de Investigaciones Científicas y Técnicas-
dc.sourceinstacron:CONICET-
dc.subjectChagas Disease-
dc.subjectdiagnosis-
dc.subjecttarget product profile-
dc.subjectdiagnosis-
dc.subjectOtras Ciencias Biológicas-
dc.subjectCiencias Biológicas-
dc.subjectCIENCIAS NATURALES Y EXACTAS-
dc.titleTarget Product Profile (TPP) for Chagas Disease Point-of-Care Diagnosis and Assessment of Response to Treatment-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.typeinfo:ar-repo/semantics/articulo-
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