Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Camara, María de los Milagros | - |
| dc.creator | Bouvier, León Alberto | - |
| dc.creator | Miranda, Mariana Reneé | - |
| dc.creator | Pereira, Claudio Alejandro | - |
| dc.date | 2017-07-13T18:20:13Z | - |
| dc.date | 2017-07-13T18:20:13Z | - |
| dc.date | 2015-01 | - |
| dc.date | 2017-07-13T17:53:47Z | - |
| dc.date.accessioned | 2019-04-29T15:40:20Z | - |
| dc.date.available | 2019-04-29T15:40:20Z | - |
| dc.date.issued | 2017-07-13T18:20:13Z | - |
| dc.date.issued | 2017-07-13T18:20:13Z | - |
| dc.date.issued | 2015-01 | - |
| dc.date.issued | 2017-07-13T17:53:47Z | - |
| dc.identifier | Camara, María de los Milagros; Bouvier, León Alberto; Miranda, Mariana Reneé; Pereira, Claudio Alejandro; The flagellar adenylate kinases of Trypanosoma cruzi; Oxford University Press; FEMS Microbiology Letters; 362; 1; 1-2015; 1-5 | - |
| dc.identifier | 0378-1097 | - |
| dc.identifier | http://hdl.handle.net/11336/20357 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/299106 | - |
| dc.description | Adenylate kinases (ADK) are key enzymes involved in cell energy management. Trypanosomatids present the highest number of variants in a single cell in comparison with the rest of the living organisms. In this work, we characterized two flagellar ADKs from Trypanosoma cruzi, called TcADK1 and TcADK4, which are also located in the cell cytosol. Interestingly, TcADK1 presents a stage-specific expression. This variant was detected in epimastigotes cells, and was completely absent in trypomastigotes and amastigotes, while TcADK4 is present in the major life cycle stages of T. cruzi. Both variants are also regulated, in opposite ways, along the parasite growth curve suggesting that their expression depends on the intra- and extracellular conditions. Both, TcADK1 and TcADK4 present N-terminal extension that could be responsible for their subcellular localization. The presence of ADK variants in the flagellum would be critical for the provision of energy in a process of high ATP consumption such as cell motility. | - |
| dc.description | Fil: Camara, María de los Milagros. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Biotecnológicas. Universidad Nacional de San Martín. Instituto de Investigaciones Biotecnológicas; Argentina | - |
| dc.description | Fil: Bouvier, León Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Biotecnológicas. Universidad Nacional de San Martín. Instituto de Investigaciones Biotecnológicas; Argentina | - |
| dc.description | Fil: Miranda, Mariana Reneé. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina | - |
| dc.description | Fil: Pereira, Claudio Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Oxford University Press | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/femsle/article/362/1/1/2467431/The-manganese-responsive-regulator-MntR-represses | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1093/femsle/fnu020 | - |
| dc.rights | info:eu-repo/semantics/restrictedAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.subject | Chagas disease | - |
| dc.subject | Trypanosoma brucei | - |
| dc.subject | Trypanosoma cruzi | - |
| dc.subject | Adenylate kinase | - |
| dc.subject | Flagellum | - |
| dc.subject | Phosphotransferase | - |
| dc.subject | Bioquímica y Biología Molecular | - |
| dc.subject | Ciencias Biológicas | - |
| dc.subject | CIENCIAS NATURALES Y EXACTAS | - |
| dc.title | The flagellar adenylate kinases of Trypanosoma cruzi | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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