Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Berdakin, Matias | - |
| dc.creator | Steinmetz, Vicent | - |
| dc.creator | Maitre, Philippe | - |
| dc.creator | Pino, Gustavo Ariel | - |
| dc.date | 2017-12-26T14:39:06Z | - |
| dc.date | 2017-12-26T14:39:06Z | - |
| dc.date | 2014-05 | - |
| dc.date | 2017-12-21T16:59:16Z | - |
| dc.date.accessioned | 2019-04-29T15:42:08Z | - |
| dc.date.available | 2019-04-29T15:42:08Z | - |
| dc.date.issued | 2014-05 | - |
| dc.identifier | Pino, Gustavo Ariel; Maitre, Philippe; Steinmetz, Vicent; Berdakin, Matias; Gas Phase Structure of Metal Mediated (Cytosine)2Ag+Mimics theHemiprotonated (Cytosine)2H+Dimer ini‑Motif Folding; American Chemical Society; Journal of Physical Chemistry A; 118; 21; 5-2014; 3804-3809 | - |
| dc.identifier | 1089-5639 | - |
| dc.identifier | http://hdl.handle.net/11336/31495 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/299922 | - |
| dc.description | The study of metal ion–DNA interaction aiming to understand the stabilization of artificial base pairing and a number of noncanonical motifs is of current interest, due to their potential exploitation in developing new technological devices and expanding the genetic code. A successful strategy has been the synthesis of metal-mediated base pairs, in which a coordinative bond to a central metal cation replaces a H-bond in a natural pair. In this work, we characterized, for the first time, the gas phase structure of the cytosine···Ag+···cytosine (C–Ag+–C) complex by means of InfraRed-MultiPhoton-Dissociation (IR-MPD) spectroscopy and theoretical calculation. The IR-spectrum was confidently assigned to one structure with the Ag+ acting as a bridge between the heteronitrogen atoms in each cytosine (both in the keto-amino form). This structure is biologically relevant since it mimics the structure of the hemiprotonated C–H+–C dimer responsible for the stabilization of the i-motif structure in DNA, with the replacement of the NH···N bond by a stronger N···Ag+···N bond. Moreover, since the structure of the C–Ag+–C complex is planar, it allows an optimum intercalation between pairs of the two antiparallel strand duplex in the DNA i-motif structure. | - |
| dc.description | Fil: Berdakin, Matias. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina | - |
| dc.description | Fil: Steinmetz, Vicent. Universite Paris Sud; Francia | - |
| dc.description | Fil: Maitre, Philippe. Universite Paris Sud; Francia | - |
| dc.description | Fil: Pino, Gustavo Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | American Chemical Society | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/http://www.pubs.acs.org/doi/abs/10.1021/jp5038969 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1021/jp5038969 | - |
| dc.rights | info:eu-repo/semantics/restrictedAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.source.uri | http://hdl.handle.net/11336/7868 | - |
| dc.subject | base-pairing | - |
| dc.subject | DNA | - |
| dc.subject | silver-bound-dimer | - |
| dc.subject | Otras Ciencias Químicas | - |
| dc.subject | Ciencias Químicas | - |
| dc.subject | CIENCIAS NATURALES Y EXACTAS | - |
| dc.title | Gas Phase Structure of Metal Mediated (Cytosine)2Ag+Mimics theHemiprotonated (Cytosine)2H+Dimer ini‑Motif Folding | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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