Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Razuc, Mariela Fernanda | - |
| dc.creator | Grunhut, Marcos | - |
| dc.creator | Garrido, Mariano Enrique | - |
| dc.creator | Fernández Band, Beatriz Susana | - |
| dc.date | 2017-12-12T19:44:15Z | - |
| dc.date | 2017-12-12T19:44:15Z | - |
| dc.date | 2014-12 | - |
| dc.date | 2017-12-12T18:43:26Z | - |
| dc.date.accessioned | 2019-04-29T15:42:17Z | - |
| dc.date.available | 2019-04-29T15:42:17Z | - |
| dc.date.issued | 2014-12 | - |
| dc.identifier | Razuc, Mariela Fernanda; Grunhut, Marcos; Garrido, Mariano Enrique; Fernández Band, Beatriz Susana; Second Order Advantage Applied to the Spectrophotometric Analysis of Ciprofloxacin and Dexamethasone in Ophthalmic Drops; Automatic Green Method Using On-line Photodegradation; Japan Society for Analytical Chemistry; Analytical Sciences; 30; 12; 12-2014; 1121-1128 | - |
| dc.identifier | 0910-6340 | - |
| dc.identifier | http://hdl.handle.net/11336/30344 | - |
| dc.identifier | 1348-2246 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/299987 | - |
| dc.description | On-line photodegradation and spectrophotometric analysis assisted by multivariate curve resolution-alternating least squares (MCR-ALS) was developed the simultaneous determination of ciprofloxacin (CIP) and dexamethasone (DEX) in ophthalmic suspensions using an automated flow-batch analysis (FBA) system. CIP and DEX have strongly overlapped UV spectra. Overcoming this lack of selectivity involves augmenting data dimensionality. This could be performed by adding information about the sample photodegradation to obtain the so-called second order advantage. Commercial sample analysis was successfully performed and no statistical differences (α = 0.05) with respect to pharmacopeia methods were obtained. The proposed method offers several advantages over the methods developed to date. In agreement with the principles of green chemistry, only water was used as solvent, low amounts of waste were generated and on-line waste treatment was included in the system. Moreover, the cost per analysis was significantly reduced compared to methods that employ separative techniques. | - |
| dc.description | Fil: Razuc, Mariela Fernanda. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina | - |
| dc.description | Fil: Grunhut, Marcos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina | - |
| dc.description | Fil: Garrido, Mariano Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina | - |
| dc.description | Fil: Fernández Band, Beatriz Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Japan Society for Analytical Chemistry | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.2116/analsci.30.1121 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/https://www.jstage.jst.go.jp/article/analsci/30/12/30_1121/_article | - |
| dc.rights | info:eu-repo/semantics/openAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.subject | PHOTODEGRADATION | - |
| dc.subject | SECOND ORDER ADVANTAGE | - |
| dc.subject | FLOW-BATCH | - |
| dc.subject | GREEN CHEMISTRY | - |
| dc.subject | CIPROFLOXACIN | - |
| dc.subject | DEXAMETHASONE | - |
| dc.subject | Otras Ciencias Químicas | - |
| dc.subject | Ciencias Químicas | - |
| dc.subject | CIENCIAS NATURALES Y EXACTAS | - |
| dc.title | Second Order Advantage Applied to the Spectrophotometric Analysis of Ciprofloxacin and Dexamethasone in Ophthalmic Drops; Automatic Green Method Using On-line Photodegradation | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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