Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Puerta Suarez, Jenniffer | - |
| dc.creator | Sanchez, Leonardo R. | - |
| dc.creator | Salazar, Florencia | - |
| dc.creator | Saka, Hector Alex | - |
| dc.creator | Molina, Rosa | - |
| dc.creator | Tissera, Andrea | - |
| dc.creator | Rivero, Virginia Elena | - |
| dc.creator | Cardona Maya, Walter D. | - |
| dc.creator | Motrich, Ruben Dario | - |
| dc.date | 2018-06-06T18:08:16Z | - |
| dc.date | 2018-06-06T18:08:16Z | - |
| dc.date | 2017-04 | - |
| dc.date | 2018-05-29T20:56:23Z | - |
| dc.date.accessioned | 2019-04-29T15:42:25Z | - |
| dc.date.available | 2019-04-29T15:42:25Z | - |
| dc.date.issued | 2017-04 | - |
| dc.identifier | Puerta Suarez, Jenniffer; Sanchez, Leonardo R.; Salazar, Florencia; Saka, Hector Alex; Molina, Rosa; et al.; Chlamydia trachomatis neither exerts deleterious effects on spermatozoa nor impairs male fertility; Nature Publishing Group; Scientific Reports; 7; 1; 4-2017 | - |
| dc.identifier | 2045-2322 | - |
| dc.identifier | http://hdl.handle.net/11336/47518 | - |
| dc.identifier | 2045-2322 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/300028 | - |
| dc.description | Chlamydia trachomatis is the most prevalent sexually transmitted bacterial infection. However, whether Chlamydia trachomatis has a negative impact on sperm quality and male fertility is still controversial. Herein, we report the effects on sperm quality of the in vitro exposure of spermatozoa to Chlamydia trachomatis, and also the effects of male genital infection on male fertility using an animal model. Human and mouse sperm were obtained from healthy donors and cauda epididimys from C57BL/6 mice, respectively. Highly motile human or mouse spermatozoa were in vitro exposed to C. trachomatis (serovar E or LGV) or C. muridarum, respectively. Then, sperm quality parameters were analyzed. Moreover, male fertility of Chlamydia muridarum infected male C57BL/6 mice was assessed. Human or murine sperm in vitro exposed to increasing bacterial concentrations or soluble factors from C. trachomatis or C. muridarum, respectively, did not show differences in sperm motility and viability, apoptosis, mitochondrial membrane potential, DNA fragmentation, ROS production and lipid peroxidation levels, when compared with control sperm (p > 0.05). Moreover, no differences in fertility parameters (potency, fecundity, fertility index, pre- and post-implantation loss) were observed between control and infected males. In conclusion, our results indicate that Chlamydia spp. neither directly exerts deleterious effects on spermatozoa nor impairs male fertility. | - |
| dc.description | Fil: Puerta Suarez, Jenniffer. Universidad de Antioquia; Colombia | - |
| dc.description | Fil: Sanchez, Leonardo R.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina | - |
| dc.description | Fil: Salazar, Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina | - |
| dc.description | Fil: Saka, Hector Alex. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina | - |
| dc.description | Fil: Molina, Rosa. Laboratorio de Andrologia y Reproduccion; Argentina | - |
| dc.description | Fil: Tissera, Andrea. Laboratorio de Andrologia y Reproduccion; Argentina | - |
| dc.description | Fil: Rivero, Virginia Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina | - |
| dc.description | Fil: Cardona Maya, Walter D.. Universidad de Antioquia; Colombia | - |
| dc.description | Fil: Motrich, Ruben Dario. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Nature Publishing Group | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/http://www.nature.com/articles/s41598-017-01262-w | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1038/s41598-017-01262-w | - |
| dc.rights | info:eu-repo/semantics/openAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.subject | CHLAMYDIA | - |
| dc.subject | SPERM | - |
| dc.subject | INFECTION | - |
| dc.subject | MALE INFERTILITY | - |
| dc.subject | Medicina Critica y de Emergencia | - |
| dc.subject | Medicina Clínica | - |
| dc.subject | CIENCIAS MÉDICAS Y DE LA SALUD | - |
| dc.title | Chlamydia trachomatis neither exerts deleterious effects on spermatozoa nor impairs male fertility | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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