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dc.creatorPiazza, Yanina Grisel-
dc.creatorPandolfi, Matias-
dc.creatorLo Nostro, Fabiana Laura-
dc.date2019-01-18T21:05:49Z-
dc.date2019-01-18T21:05:49Z-
dc.date2011-08-
dc.date2019-01-17T13:57:54Z-
dc.date.accessioned2019-04-29T15:43:24Z-
dc.date.available2019-04-29T15:43:24Z-
dc.date.issued2011-08-
dc.identifierPiazza, Yanina Grisel; Pandolfi, Matias; Lo Nostro, Fabiana Laura; Effect of the organochlorine pesticide endosulfan on GnRH and gonadotrope cell populations in fish larvae; Springer; Archives of Environmental Contamination and Toxicology; 61; 2; 8-2011; 300-310-
dc.identifier0090-4341-
dc.identifierhttp://hdl.handle.net/11336/68272-
dc.identifier1432-0703-
dc.identifierCONICET Digital-
dc.identifierCONICET-
dc.identifier.urihttp://rodna.bn.gov.ar:8080/jspui/handle/bnmm/300338-
dc.descriptionEndocrine-disrupting chemicals can influence the hypothalamus-pituitary- gonad axis and possibly affect reproduction in vertebrates. We analyzed the effect of 30-day endosulfan (ES) exposure in sexually undifferentiated larvae of the cichlid fish Cichlasoma dimerus. The number, area, mean cytoplasmic and nuclear diameter, and mean cytoplasmic optical density of gonadotropin-releasing hormone (GnRH) I, II, and III immunoreactive (ir-) neurons and β follicle-stimulating hormone (βFSH) ir-cells were measured. Animals exposed to the highest ES concentration (0.1 μg/l) showed a decrease in GnRH I nucleus/cytoplasm area ratio upon exposure. Nuclear area and mean nuclear diameter of βFSH ir-cells was higher in ES treated fish. βFSH nucleus/cytoplasm area ratio was high in exposed animals, and animals exposed to 0.1 μg/l ES showed smaller mean cytoplasmic optical density. These findings suggest that ES affects GnRH I and βFSH protein synthesis/release. However, these responses seem to be insufficient to affect gonadal differentiation at this stage of development.-
dc.descriptionFil: Piazza, Yanina Grisel. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina-
dc.descriptionFil: Pandolfi, Matias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina-
dc.descriptionFil: Lo Nostro, Fabiana Laura. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina-
dc.formatapplication/pdf-
dc.formatapplication/pdf-
dc.languageeng-
dc.publisherSpringer-
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/s00244-010-9621-3-
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs00244-010-9621-3-
dc.rightsinfo:eu-repo/semantics/restrictedAccess-
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/-
dc.sourcereponame:CONICET Digital (CONICET)-
dc.sourceinstname:Consejo Nacional de Investigaciones Científicas y Técnicas-
dc.sourceinstacron:CONICET-
dc.subjectFSH-
dc.subjectGnRH-
dc.subjectCichlids-
dc.subjectEndocrine disruptors-
dc.subjectOtras Ciencias Biológicas-
dc.subjectCiencias Biológicas-
dc.subjectCIENCIAS NATURALES Y EXACTAS-
dc.titleEffect of the organochlorine pesticide endosulfan on GnRH and gonadotrope cell populations in fish larvae-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.typeinfo:ar-repo/semantics/articulo-
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