Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.provenance | CONICET | - |
| dc.creator | Pérez, Denisa Soledad | - |
| dc.creator | Martínez, Guadalupe | - |
| dc.creator | Soraci, Alejandro Luis | - |
| dc.creator | Tapia, Maria Ofelia | - |
| dc.date | 2016-03-08T20:21:10Z | - |
| dc.date | 2016-03-08T20:21:10Z | - |
| dc.date | 2013-04 | - |
| dc.date | 2016-03-30 10:35:44.97925-03 | - |
| dc.date.accessioned | 2019-04-29T15:45:17Z | - |
| dc.date.available | 2019-04-29T15:45:17Z | - |
| dc.date.issued | 2013-04 | - |
| dc.identifier | Pérez, Denisa Soledad; Martínez, Guadalupe; Soraci, Alejandro Luis; Tapia, Maria Ofelia; In vitro penetration of the antibiotic fosfomycin in swine intestinal cells (IPEC J2); Radiance Research Academy; International Journal of Medical and Pharmaceutical Sciences; 4; 2; 4-2013; 6-16 | - |
| dc.identifier | 2231- 2188 | - |
| dc.identifier | http://hdl.handle.net/11336/4689 | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/301173 | - |
| dc.description | Fosfomycin is an antibiotic widely used for the treatment and prevention of swine infections caused by resistant bacteria. The aim of this research was to study the penetration of fosfomycin in an in vitro model of intestinal cells (IPEC-J2 cells). Cells cultures were subjected to 580 μg/mL of calcium fosfomycin. Intracellular concentrations of the antibiotic were analyzed by HPLC MS/MS and they ranged from 23.48 to 45.81 μg/mL (Tmax: 4 h). Fosfomycin concentrations exceeded the MIC90 for the most important pathogens in swine intestinal infections (Escherichia coli: 0.50 μg/mL, Salmonella enterica subsp. Enterica: 4 μg/mL). Therefore, it is apparent that fosfomycin is an alternative for the treatment of intestinal infections in pigs | - |
| dc.description | Fil: Pérez, Denisa Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tandil. Centro de Investigacion Veterinaria de Tandil; Argentina | - |
| dc.description | Fil: Martínez, Guadalupe. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tandil. Centro de Investigacion Veterinaria de Tandil; Argentina | - |
| dc.description | Fil: Soraci, Alejandro Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tandil. Centro de Investigacion Veterinaria de Tandil; Argentina | - |
| dc.description | Fil: Tapia, Maria Ofelia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tandil. Centro de Investigacion Veterinaria de Tandil; Argentina | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Radiance Research Academy | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/http://www.scopemed.org/?mno=48472 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/issn/2231- 2188 | - |
| dc.rights | info:eu-repo/semantics/openAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.source.uri | http://hdl.handle.net/11336/4689 | - |
| dc.subject | Fosfomycin | - |
| dc.subject | In vitro | - |
| dc.subject | Penetration, IPEC | - |
| dc.subject | Intestinal infections, pigs | - |
| dc.subject | Ciencias Veterinarias | - |
| dc.subject | Ciencias Veterinarias | - |
| dc.subject | CIENCIAS AGRÍCOLAS | - |
| dc.title | In vitro penetration of the antibiotic fosfomycin in swine intestinal cells (IPEC J2) | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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