Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.provenance | CONICET | - |
| dc.creator | Errasti, María Eugenia | - |
| dc.creator | Caffini, Nestor Oscar | - |
| dc.creator | Pelzer, Lilian Eugenia | - |
| dc.creator | Rotelli, Alejandra Ester | - |
| dc.date | 2017-08-04T22:02:38Z | - |
| dc.date | 2017-08-04T22:02:38Z | - |
| dc.date | 2013-01 | - |
| dc.date | 2017-07-28T15:03:36Z | - |
| dc.date.accessioned | 2019-04-29T15:47:31Z | - |
| dc.date.available | 2019-04-29T15:47:31Z | - |
| dc.date.issued | 2013-01 | - |
| dc.identifier | Errasti, María Eugenia; Caffini, Nestor Oscar; Pelzer, Lilian Eugenia; Rotelli, Alejandra Ester; Anti-inflammatory Activity of Bromelia hieronymi: Comparison with Bromelain; Georg Thieme Verlag Kg; Planta Medica; 79; 3-4; 1-2013; 207-213 | - |
| dc.identifier | 0032-0943 | - |
| dc.identifier | http://hdl.handle.net/11336/21938 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/302112 | - |
| dc.description | Some plant proteases (e. g., papain, bromelain, ficin) have been used as anti-inflammatory agents for some years, and especially bromelain is still being used as alternative and/or complementary therapy to glucocorticoids, nonsteroidal antirheumatics, and immunomodulators. Bromelain is an extract rich in cysteine endopeptidases obtained from Ananas comosus. In this study the anti-inflammatory action of a partially purified extract of Bromelia hieronymi fruits, whose main components are cysteine endopeptidases, is presented. Different doses of a partially purified extract of B. hieronymi were assayed on carrageenan-induced and serotonine-induced rat paw edema, as well as in cotton pellet granuloma model. Doses with equal proteolytic activity of the partially purified extract and bromelain showed significantly similar anti-inflammatory responses. Treatment of the partially purified extract and bromelain with E-64 provoked loss of anti-inflammatory activity on carrageenan-induced paw edema, a fact which is consistent with the hypothesis that the proteolytic activity would be responsible for the anti-inflammatory action. | - |
| dc.description | Fil: Errasti, María Eugenia. Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Departamento de Ciencias Biologicas. Laboratorio de Investigacion de Proteinas Vegetales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina | - |
| dc.description | Fil: Caffini, Nestor Oscar. Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Departamento de Ciencias Biologicas. Laboratorio de Investigacion de Proteinas Vegetales; Argentina | - |
| dc.description | Fil: Pelzer, Lilian Eugenia. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina | - |
| dc.description | Fil: Rotelli, Alejandra Ester. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Georg Thieme Verlag Kg | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1055/s-0032-1328201 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/https://www.thieme-connect.de/DOI/DOI?10.1055/s-0032-1328201 | - |
| dc.rights | info:eu-repo/semantics/restrictedAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.source.uri | http://hdl.handle.net/11336/21938 | - |
| dc.subject | Bromelia hieronymi | - |
| dc.subject | Bromeliaceae | - |
| dc.subject | Bromelain | - |
| dc.subject | Anti-inflammatory | - |
| dc.subject | Plant proteases | - |
| dc.subject | Ciencias de las Plantas, Botánica | - |
| dc.subject | Ciencias Biológicas | - |
| dc.subject | CIENCIAS NATURALES Y EXACTAS | - |
| dc.subject | Farmacología y Farmacia | - |
| dc.subject | Medicina Básica | - |
| dc.subject | CIENCIAS MÉDICAS Y DE LA SALUD | - |
| dc.title | Anti-inflammatory Activity of Bromelia hieronymi: Comparison with Bromelain | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
Ficheros en este ítem:
No hay ficheros asociados a este ítem.