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dc.provenanceCONICET-
dc.creatorBesuhli, Valeria-
dc.creatorde Laurentiis, Andrea-
dc.creatorLes Dees, W.-
dc.creatorEndruhn, Axel-
dc.creatorRettori, Valeria-
dc.date2017-03-07T20:16:04Z-
dc.date2017-03-07T20:16:04Z-
dc.date2014-02-
dc.date2017-03-06T15:25:43Z-
dc.date.accessioned2019-04-29T15:47:42Z-
dc.date.available2019-04-29T15:47:42Z-
dc.date.issued2014-02-
dc.identifierBesuhli, Valeria; de Laurentiis, Andrea; Les Dees, W.; Endruhn, Axel ; Rettori, Valeria; Host neuro-immuno-endocrine responses in Periodontal Disease; Bentham Science Publishers; Current Pharmaceutical Design.; 20; 29; 2-2014; 4749-4759-
dc.identifier1381-6128-
dc.identifierhttp://hdl.handle.net/11336/13607-
dc.identifier.urihttp://rodna.bn.gov.ar:8080/jspui/handle/bnmm/302205-
dc.descriptionPeriodontitis is a chronic inflammatory complex disease caused by microorganisms. It may be influenced by diverse systemic disorders, environmental, genetic and socio-psychological factors with the ability to alter the balance of the host neuro-immunoendocrine responses. It is characterized by the progressive destruction of the tooth supporting apparatus leading to tooth loss, with possible impact on general health. Starting with a brief description of the periodontium, etiopathogenesis, repair processes and several physiological mechanisms and their disarray on periodontium response to bacterial challenge. Following, the negative effects of stress on the disease and some remarks on the recently discovered effects of oxytocin that modulate stress response and its role in individual coping mechanisms to stress. We also focus on the participation of components and functions of endocannabinoid system with anti-inflammatory actions on gingiva. Finally, a discussion that may link between diabetes, cardiovascular diseases, stroke and metabolic syndrome associated with periodontal disease; all of them sharing a common denominator that is inflammation and oxidative stress.-
dc.descriptionFil: Besuhli, Valeria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos; Argentina. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Universidad Maimonides; Argentina-
dc.descriptionFil: de Laurentiis, Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos; Argentina. Universidad de Buenos Aires. Facultad de Medicina; Argentina-
dc.descriptionFil: Les Dees, W.. Texas AyM University; Estados Unidos-
dc.descriptionFil: Endruhn, Axel. Universidad Maimonides; Argentina-
dc.descriptionFil: Rettori, Valeria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos; Argentina-
dc.formatapplication/pdf-
dc.formatapplication/pdf-
dc.languageeng-
dc.publisherBentham Science Publishers-
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://www.eurekaselect.com/120069/article-
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.2174/1381612820666140130204043-
dc.rightsinfo:eu-repo/semantics/restrictedAccess-
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/-
dc.sourcereponame:CONICET Digital (CONICET)-
dc.sourceinstname:Consejo Nacional de Investigaciones Científicas y Técnicas-
dc.sourceinstacron:CONICET-
dc.source.urihttp://hdl.handle.net/11336/13607-
dc.subjectgingiva-
dc.subjectneuropeptides-
dc.subjectinflammation-
dc.subjectstress-
dc.subjectendocannabinoids-
dc.subjectcytokines-
dc.subjectOtras Ciencias de la Salud-
dc.subjectCiencias de la Salud-
dc.subjectCIENCIAS MÉDICAS Y DE LA SALUD-
dc.titleHost neuro-immuno-endocrine responses in Periodontal Disease-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.typeinfo:ar-repo/semantics/articulo-
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