Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Riafrecha, Leonardo Ezequiel | - |
| dc.creator | Vullo, Daniela | - |
| dc.creator | Ouahrani Bettache, Safia | - |
| dc.creator | Köhler, Stephan | - |
| dc.creator | Dumy, Pascal | - |
| dc.creator | Winum, Jean Yves | - |
| dc.creator | Supuran, Claudiu T. | - |
| dc.creator | Colinas, Pedro Alfonso | - |
| dc.date | 2018-07-31T20:17:22Z | - |
| dc.date | 2018-07-31T20:17:22Z | - |
| dc.date | 2015-11 | - |
| dc.date | 2018-07-31T17:18:05Z | - |
| dc.date.accessioned | 2019-04-29T15:49:03Z | - |
| dc.date.available | 2019-04-29T15:49:03Z | - |
| dc.date.issued | 2015-11 | - |
| dc.identifier | Riafrecha, Leonardo Ezequiel; Vullo, Daniela; Ouahrani Bettache, Safia; Köhler, Stephan; Dumy, Pascal; et al.; Inhibition of β-carbonic anhydrases from Brucella suis with C-cinnamoyl glycosides incorporating the phenol moiety; Taylor & Francis; Journal of Enzyme Inhibition and Medicinal Chemistry; 30; 6; 11-2015; 1017-1020 | - |
| dc.identifier | 1475-6366 | - |
| dc.identifier | http://hdl.handle.net/11336/53673 | - |
| dc.identifier | 1475-6374 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/302836 | - |
| dc.description | A small series of C-glycosides containing the phenol moiety was tested for the inhibition of the β-class carbonic anhydrases (βCAs, EC 4.2.1.1) from Brucella suis. Many compounds showed activities in the micromolar or submicromolar range and excellent selectivity for pathogen CAs over human isozymes. Glycosides incorporating the 3-hydroxyphenyl moiety showed the best inhibition profile, and therefore this functionality represents lead for the development of novel anti-infectives with a new mechanism of action. | - |
| dc.description | Fil: Riafrecha, Leonardo Ezequiel. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química. Laboratorio de Estudio de Compuestos Orgánicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina | - |
| dc.description | Fil: Vullo, Daniela. Università degli Studi di Firenze; Italia | - |
| dc.description | Fil: Ouahrani Bettache, Safia. Université Montpellier II; Francia | - |
| dc.description | Fil: Köhler, Stephan. Université Montpellier II; Francia | - |
| dc.description | Fil: Dumy, Pascal. Ecole Nationale Supe´rieure de Chimie de Montpellier; Fiyi | - |
| dc.description | Fil: Winum, Jean Yves. Ecole Nationale Supe´rieure de Chimie de Montpellier; Fiyi | - |
| dc.description | Fil: Supuran, Claudiu T.. Università degli Studi di Firenze; Italia | - |
| dc.description | Fil: Colinas, Pedro Alfonso. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química. Laboratorio de Estudio de Compuestos Orgánicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Taylor & Francis | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3109/14756366.2014.986120 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/full/10.3109/14756366.2014.986120 | - |
| dc.rights | info:eu-repo/semantics/restrictedAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.source.uri | http://hdl.handle.net/11336/65406 | - |
| dc.subject | ANTIBACTERIAL | - |
| dc.subject | CARBOHYDRATE | - |
| dc.subject | CARBONIC ANHYDRASE | - |
| dc.subject | Otras Ciencias Químicas | - |
| dc.subject | Ciencias Químicas | - |
| dc.subject | CIENCIAS NATURALES Y EXACTAS | - |
| dc.title | Inhibition of β-carbonic anhydrases from Brucella suis with C-cinnamoyl glycosides incorporating the phenol moiety | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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