Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Bolzan, Alejandro Daniel | - |
| dc.date | 2018-12-04T17:15:22Z | - |
| dc.date | 2018-12-04T17:15:22Z | - |
| dc.date | 2017-07 | - |
| dc.date | 2018-10-22T21:50:29Z | - |
| dc.date.accessioned | 2019-04-29T15:49:56Z | - |
| dc.date.available | 2019-04-29T15:49:56Z | - |
| dc.date.issued | 2017-07 | - |
| dc.identifier | Bolzan, Alejandro Daniel; Interstitial telomeric sequences in vertebrate chromosomes: Origin, function, instability and evolution; Elsevier Science; Mutation Research. Reviews In Mutation Research; 773; 7-2017; 51-65 | - |
| dc.identifier | 1383-5742 | - |
| dc.identifier | http://hdl.handle.net/11336/65723 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/303216 | - |
| dc.description | By definition, telomeric sequences are located at the very ends or terminal regions of chromosomes. However, several vertebrate species show blocks of (TTAGGG)n repeats present in non-terminal regions of chromosomes, the so-called interstitial telomeric sequences (ITSs), interstitial telomeric repeats or interstitial telomeric bands, which include those intrachromosomal telomeric-like repeats located near (pericentromeric ITSs) or within the centromere (centromeric ITSs) and those telomeric repeats located between the centromere and the telomere (i.e., truly interstitial telomeric sequences) of eukaryotic chromosomes. According with their sequence organization, localization and flanking sequences, ITSs can be classified into four types: 1) short ITSs, 2) subtelomeric ITSs, 3) fusion ITSs, and 4) heterochromatic ITSs. The first three types have been described mainly in the human genome, whereas heterochromatic ITSs have been found in several vertebrate species but not in humans. Several lines of evidence suggest that ITSs play a significant role in genome instability and evolution. This review aims to summarize our current knowledge about the origin, function, instability and evolution of these telomeric-like repeats in vertebrate chromosomes. | - |
| dc.description | Fil: Bolzan, Alejandro Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Elsevier Science | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1016/j.mrrev.2017.04.002 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1383574216301533 | - |
| dc.rights | info:eu-repo/semantics/restrictedAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.subject | CHROMOSOMAL ABERRATIONS | - |
| dc.subject | CHROMOSOME INSTABILITY | - |
| dc.subject | GENOME INSTABILITY | - |
| dc.subject | INTERSTITIAL TELOMERIC REPEATS | - |
| dc.subject | KARYOTYPIC EVOLUTION | - |
| dc.subject | TELOMERE | - |
| dc.subject | Otras Ciencias Biológicas | - |
| dc.subject | Ciencias Biológicas | - |
| dc.subject | CIENCIAS NATURALES Y EXACTAS | - |
| dc.title | Interstitial telomeric sequences in vertebrate chromosomes: Origin, function, instability and evolution | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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