Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Bun Wong, Thomas Chi | - |
| dc.creator | Rebbert, Martha | - |
| dc.creator | Wang, Chengdong | - |
| dc.creator | Chen, Xiongfong | - |
| dc.creator | Heffer, Alison | - |
| dc.creator | Zarelli, Valeria Eugenia Paola | - |
| dc.creator | Dawid, Igor B. | - |
| dc.creator | Zhao, Hui | - |
| dc.date | 2018-06-15T22:09:49Z | - |
| dc.date | 2018-06-15T22:09:49Z | - |
| dc.date | 2016-04 | - |
| dc.date | 2018-06-13T16:52:20Z | - |
| dc.date.accessioned | 2019-04-29T15:49:58Z | - |
| dc.date.available | 2019-04-29T15:49:58Z | - |
| dc.date.issued | 2016-04 | - |
| dc.identifier | Bun Wong, Thomas Chi; Rebbert, Martha; Wang, Chengdong; Chen, Xiongfong; Heffer, Alison; et al.; Genes regulated by potassium channel tetramerization domain containing 15 (Kctd15) in the developing neural crest; U B C Press; International Journal Of Developmental Biology; 60; 4-6; 4-2016; 159-166 | - |
| dc.identifier | 0214-6282 | - |
| dc.identifier | http://hdl.handle.net/11336/48923 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/303227 | - |
| dc.description | Neural crest (NC) development is controlled precisely by a regulatory network with multiple signaling pathways and the involvement of many genes. The integration and coordination of these factors are still incompletely understood. Overexpression of Wnt3a and the BMP antagonist Chordin in animal cap cells from Xenopus blastulae induces a large number of NC specific genes. We previously suggested that Potassium Channel Tetramerization Domain containing 15 (Kctd15) regulates NC formation by affecting Wnt signaling and the activity of transcription factor AP-2. In order to advance understanding of the function of Kctd15 during NC development, we performed DNA microarray assays in explants injected with Wnt3a and Chordin, and identified genes that are affected by Kctd15 overexpression. Among the many genes identified, we chose Duf domain containing protein 1 (ddcp1), Platelet-Derived Growth Factor Receptor a (pdgfra), Complement factor properdin (cfp), Zinc Finger SWIM-Type Containing 5 (zswim5), and complement component 3 (C3) to examine their expression by whole mount in situ hybridization. Our work points to a possible role for Kctd15 in the regulation of NC formation and other steps in embryonic development. | - |
| dc.description | Fil: Bun Wong, Thomas Chi. The Chinese University of Hong Kong; China | - |
| dc.description | Fil: Rebbert, Martha. National Institutes of Health; Estados Unidos | - |
| dc.description | Fil: Wang, Chengdong. The Chinese University of Hong Kong; China | - |
| dc.description | Fil: Chen, Xiongfong. National Institutes of Health; Estados Unidos | - |
| dc.description | Fil: Heffer, Alison. National Institutes of Health; Estados Unidos | - |
| dc.description | Fil: Zarelli, Valeria Eugenia Paola. National Institutes of Health; Estados Unidos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Cienicas Médicas. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos; Argentina | - |
| dc.description | Fil: Dawid, Igor B.. National Institutes of Health; Estados Unidos | - |
| dc.description | Fil: Zhao, Hui. The Chinese University of Hong Kong; China. Chinese Academy of Sciences; República de China | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | U B C Press | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/http://www.ijdb.ehu.es/web/paper.php?doi=160058id | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1387/ijdb.160058id | - |
| dc.rights | info:eu-repo/semantics/openAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.subject | DNA MICROARRAY | - |
| dc.subject | GENE REGULATION | - |
| dc.subject | KCTD15 | - |
| dc.subject | NEURAL CREST | - |
| dc.subject | TRANSCRIPTION FACTOR AP-2 | - |
| dc.subject | XENOPUS | - |
| dc.subject | Otras Ciencias Biológicas | - |
| dc.subject | Ciencias Biológicas | - |
| dc.subject | CIENCIAS NATURALES Y EXACTAS | - |
| dc.title | Genes regulated by potassium channel tetramerization domain containing 15 (Kctd15) in the developing neural crest | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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