Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | De Palma, Giada | - |
| dc.creator | Nadal, Inmaculada | - |
| dc.creator | Medina, Marcela Susana | - |
| dc.creator | Donat, Ester | - |
| dc.creator | Ribes Koninckx, Carmen | - |
| dc.creator | Calabuig, Miguel | - |
| dc.creator | Sanz, Yolanda | - |
| dc.date | 2018-09-07T19:26:48Z | - |
| dc.date | 2018-09-07T19:26:48Z | - |
| dc.date | 2010-02-24 | - |
| dc.date | 2018-04-10T14:05:29Z | - |
| dc.date.accessioned | 2019-04-29T15:50:22Z | - |
| dc.date.available | 2019-04-29T15:50:22Z | - |
| dc.date.issued | 2010-02-24 | - |
| dc.identifier | De Palma, Giada; Nadal, Inmaculada; Medina, Marcela Susana; Donat, Ester; Ribes Koninckx, Carmen; et al.; Intestinal dysbiosis and reduced immunoglobulin-coated bacteria associated with coeliac disease in children; BioMed Central; BMC Microbiology; 10; 63; 24-2-2010; 1-7 | - |
| dc.identifier | 1471-2180 | - |
| dc.identifier | http://hdl.handle.net/11336/58811 | - |
| dc.identifier | 1471-2180 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/303393 | - |
| dc.description | Background. Coeliac disease is a chronic intestinal inflammatory disorder due to an aberrant immune response to dietary gluten proteins in genetically predisposed individuals. Mucosal immune response through IgA secretion constitutes a first line of defence responsible for neutralizing noxious antigens and pathogens. The aim of this study was the characterization of the relationships between immunoglobulin-coated bacteria and bacterial composition of faeces of coeliac disease (CD) patients, untreated and treated with a gluten-free diet (GFD) and healthy controls. Results. IgA-coated faecal bacterial levels were significantly lower in both untreated and treated CD patients than in healthy controls. IgG and IgM-coated bacterial levels were also significantly lower in treated CD patients than in untreated CD patients and controls. Gram-positive to Gram-negative bacteria ratio was significantly reduced in both CD patients compared to controls. Bifidobacterium, Clostridium histolyticum, C. lituseburense and Faecalibacterium prausnitzii group proportions were less abundant (P < 0.050) in untreated CD patients than in healthy controls. Bacteroides-Prevotella group proportions were more abundant (P < 0.050) in untreated CD patients than in controls. Levels of IgA coating the Bacteroides-Prevotella group were significantly reduced (P < 0.050) in both CD patients in comparison with healthy controls. Conclusions. In CD patients, reduced IgA-coated bacteria is associated with intestinal dysbiosis, which altogether provide new insights into the possible relationships between the gut microbiota and the host defences in this disorder. | - |
| dc.description | Fil: De Palma, Giada. Consejo Superior de Investigaciones Científicas. Instituto de Agroquímica y Tecnología de Alimentos; España | - |
| dc.description | Fil: Nadal, Inmaculada. Consejo Superior de Investigaciones Científicas. Instituto de Agroquímica y Tecnología de Alimentos; España | - |
| dc.description | Fil: Medina, Marcela Susana. Consejo Superior de Investigaciones Científicas. Instituto de Agroquímica y Tecnología de Alimentos; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina | - |
| dc.description | Fil: Donat, Ester. Hospital Universitario La Fe de Valencia; España | - |
| dc.description | Fil: Ribes Koninckx, Carmen. Hospital Universitario La Fe de Valencia; España | - |
| dc.description | Fil: Calabuig, Miguel. Hospital General Universitario de Valencia; España | - |
| dc.description | Fil: Sanz, Yolanda. Consejo Superior de Investigaciones Científicas. Instituto de Agroquímica y Tecnología de Alimentos; España | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | BioMed Central | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1186/1471-2180-10-63 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/https://bmcmicrobiol.biomedcentral.com/articles/10.1186/1471-2180-10-63 | - |
| dc.rights | info:eu-repo/semantics/openAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.subject | CELIAC DISEASE | - |
| dc.subject | PROBIOTIC | - |
| dc.subject | IMMUNOGLOBULIN-COATED BACTERIA | - |
| dc.subject | BIFIDOBACTERIA | - |
| dc.subject | Salud Ocupacional | - |
| dc.subject | Ciencias de la Salud | - |
| dc.subject | CIENCIAS MÉDICAS Y DE LA SALUD | - |
| dc.title | Intestinal dysbiosis and reduced immunoglobulin-coated bacteria associated with coeliac disease in children | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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