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dc.creatorBarttfeld, Pablo-
dc.creatorBekinschtein, Tristán Andrés-
dc.creatorSalles, Alejo-
dc.creatorAgú, Emanuel José-
dc.creatorAdapa, Ram-
dc.creatorMenon, David-
dc.creatorSigman, Mariano-
dc.date2018-06-08T17:05:59Z-
dc.date2018-06-08T17:05:59Z-
dc.date2015-12-
dc.date2018-05-21T17:22:35Z-
dc.date.accessioned2019-04-29T15:50:47Z-
dc.date.available2019-04-29T15:50:47Z-
dc.date.issued2015-12-
dc.identifierBarttfeld, Pablo; Bekinschtein, Tristán Andrés; Salles, Alejo; Agú, Emanuel José; Adapa, Ram; et al.; Factoring the brain signatures of anesthesia concentration and level of arousal across individuals; Academic Press Inc Elsevier Science; Neuroimage; 9; 12-2015; 1-7-
dc.identifier1053-8119-
dc.identifierhttp://hdl.handle.net/11336/47878-
dc.identifierCONICET Digital-
dc.identifierCONICET-
dc.identifier.urihttp://rodna.bn.gov.ar:8080/jspui/handle/bnmm/303565-
dc.descriptionCombining resting-state functional magnetic resonance imaging (fMRI) connectivity and behavioral analysis during sedation, we factored out general effects of the anesthetic drug propofol and a specific index of conscious report, participants? level of responsiveness. The factorial analysis shows that increasing concentration of propofol in blood specifically decreases the connectivity strength of fronto-parietal cortical loops. In contrast, loss of responsiveness is indexed by a functional disconnection between the thalamus and the frontal cortex, balanced by an increase in connectivity strength of the thalamus to the occipital and temporal regions of the cortex.-
dc.descriptionFil: Barttfeld, Pablo. Universidad Torcuato Di Tella; Argentina-
dc.descriptionFil: Bekinschtein, Tristán Andrés. University of Cambridge; Reino Unido-
dc.descriptionFil: Salles, Alejo. Universidad Torcuato Di Tella; Argentina-
dc.descriptionFil: Agú, Emanuel José. University of Cambridge; Estados Unidos-
dc.descriptionFil: Adapa, Ram. University of Cambridge; Estados Unidos-
dc.descriptionFil: Menon, David. University of Cambridge; Estados Unidos-
dc.descriptionFil: Sigman, Mariano. Universidad Torcuato Di Tella; Argentina-
dc.formatapplication/pdf-
dc.formatapplication/pdf-
dc.languageeng-
dc.publisherAcademic Press Inc Elsevier Science-
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S2213158215001515-
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.nicl.2015.08.013-
dc.rightsinfo:eu-repo/semantics/restrictedAccess-
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/-
dc.sourcereponame:CONICET Digital (CONICET)-
dc.sourceinstname:Consejo Nacional de Investigaciones Científicas y Técnicas-
dc.sourceinstacron:CONICET-
dc.subjectfunctional connectivity-
dc.titleFactoring the brain signatures of anesthesia concentration and level of arousal across individuals-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.typeinfo:ar-repo/semantics/articulo-
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