Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Cao, Gabriel Fernando | - |
| dc.creator | Gómez Llambí de Oromí, Hernán Jorge | - |
| dc.creator | Muller, Angelica del Carmen | - |
| dc.creator | Ottaviano, Graciela Mabel | - |
| dc.date | 2017-12-11T18:54:53Z | - |
| dc.date | 2017-12-11T18:54:53Z | - |
| dc.date | 2014-03 | - |
| dc.date | 2017-12-11T16:46:07Z | - |
| dc.date.accessioned | 2019-04-29T15:50:49Z | - |
| dc.date.available | 2019-04-29T15:50:49Z | - |
| dc.date.issued | 2014-03 | - |
| dc.identifier | Cao, Gabriel Fernando; Gómez Llambí de Oromí, Hernán Jorge; Muller, Angelica del Carmen; Ottaviano, Graciela Mabel; Rosuvastatin increases myocardial microvessels in SHR rats. Role of thioredoxin-1 and peroxiredoxin-2 expression; Elsevier Ireland; International Journal of Cardiology; 174; 1; 3-2014; 153-155 | - |
| dc.identifier | 0167-5273 | - |
| dc.identifier | http://hdl.handle.net/11336/30180 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/303582 | - |
| dc.description | Beyond their lipid-lowering action, rosuvastatin possesses pleiotropic effects including anti-inflammatory, pro-angiogenic, antioxidant effects and protective actions against endothelial dysfunction [1,2]. The spontaneously hypertensive rats (SHR) have been extensively studied as a model of essential hypertension. Analogous to that seen in humans, prolonged periods of hypertension produce left ventricular (LV) remodeling, hypertrophy and oxidative stress. Thioredoxin (Trx) and peroxiredoxin (Prx) are a ubiquitous family of cysteine-dependent antioxidant proteins, present in mammalian cells including the heart. Several reports exist in the literature indicating that these proteins are induced by oxidative stress [3]. We investigated the possible effect of long-term monotherapy with rosuvastatin in myocardial expression of redoxins and vascular endothelial growth factor (VEGF), and their relations with LV remodeling in adult SHR. Eight-week-old male SHR and Wistar-Kyoto (WKY) rats, were divided into three groups: SHR (n = 20), SHR-R (n = 20; rosuvastatin 10 mg/kg/day) and WKY (n = 20). | - |
| dc.description | Fil: Cao, Gabriel Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina | - |
| dc.description | Fil: Gómez Llambí de Oromí, Hernán Jorge. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina | - |
| dc.description | Fil: Muller, Angelica del Carmen. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina | - |
| dc.description | Fil: Ottaviano, Graciela Mabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Elsevier Ireland | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0167527314006020 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.ijcard.2014.03.166 | - |
| dc.rights | info:eu-repo/semantics/restrictedAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.subject | ANTIOXIDANT EFFECT | - |
| dc.subject | HEART | - |
| dc.subject | ROSUVASTATIN | - |
| dc.subject | SPONTANEOUSLY HYPERTENSIVE RAT | - |
| dc.subject | Inmunología | - |
| dc.subject | Medicina Básica | - |
| dc.subject | CIENCIAS MÉDICAS Y DE LA SALUD | - |
| dc.title | Rosuvastatin increases myocardial microvessels in SHR rats. Role of thioredoxin-1 and peroxiredoxin-2 expression | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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