Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Cristofolini, Andrea Lorena | - |
| dc.creator | Sanchis, Eva Gabriela | - |
| dc.creator | Moliva, Melina Vanesa | - |
| dc.creator | Alonso, L. | - |
| dc.creator | Chanique, A. | - |
| dc.creator | Koncurat, Mirta Adriana | - |
| dc.creator | Merkis, Cecilia Inés | - |
| dc.date | 2017-08-18T19:35:11Z | - |
| dc.date | 2017-08-18T19:35:11Z | - |
| dc.date | 2013-02 | - |
| dc.date | 2017-08-18T15:00:23Z | - |
| dc.date.accessioned | 2019-04-29T15:50:57Z | - |
| dc.date.available | 2019-04-29T15:50:57Z | - |
| dc.date.issued | 2013-02 | - |
| dc.identifier | Cristofolini, Andrea Lorena; Sanchis, Eva Gabriela; Moliva, Melina Vanesa; Alonso, L.; Chanique, A.; et al.; Cellular Remodelling by Apoptosis During Porcine Placentation; Wiley VCH Verlag; Reproduction in Domestic Animals; 48; 4; 2-2013; 584-590 | - |
| dc.identifier | 0936-6768 | - |
| dc.identifier | http://hdl.handle.net/11336/22698 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/303639 | - |
| dc.description | The mechanisms that regulate the apoptosis are essential to the normal development and maintenance of homoeostasis and play an important role in placental development in mammals. During porcine pregnancy, there must be a proper cellular remodelling to achieve a normal gestational development. Knowledge of pig physiology during pregnancy will explore options to increase the productivity of this species of high economical value. The purpose of this work was to study the cell morphology and apoptosis of porcine placentas from early, mid and late pregnancy. For that purpose, highresolution light microscopy and transmission electron microscopy were performed to the study of cell morphology. TUNEL, the apoptosis index (IAp) and the expression of c-FLIP through immunohistochemistry technique were used to the study of apoptosis. High-resolution light microscopy and transmission electron microscopy confirmed the presence of placental cells with ultrastructural apoptotic features. Apoptotic nuclei were detected by TUNEL in different placental structures and phagocytes containing apoptotic bodies. The IAp in villi was 9.34% at early, 0.82% at mid and 23.85% at late pregnancy. Statistically significant differences were found between periods (p < 0.05). In previous studies, we determined a differential induction of the apoptotic routes in the placental villi in agreement with the gestational period. A co-expression of receptors and mitochondrial proteins in placental connective tissue was detected, but the immunolocalization of c-FLIP would indicate an endogenous inhibition of the extrinsic pathway. In conclusion, in swine there exists differential activation of inducing apoptotic pathways in different placental structures according to the gestational period. | - |
| dc.description | Fil: Cristofolini, Andrea Lorena. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina | - |
| dc.description | Fil: Sanchis, Eva Gabriela. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina | - |
| dc.description | Fil: Moliva, Melina Vanesa. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina | - |
| dc.description | Fil: Alonso, L.. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria; Argentina | - |
| dc.description | Fil: Chanique, A.. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria; Argentina | - |
| dc.description | Fil: Koncurat, Mirta Adriana. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria; Argentina | - |
| dc.description | Fil: Merkis, Cecilia Inés. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria; Argentina | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Wiley VCH Verlag | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1111/rda.12130 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1111/rda.12130/abstract | - |
| dc.rights | info:eu-repo/semantics/restrictedAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.subject | PORCINE | - |
| dc.subject | PLACENTA | - |
| dc.subject | APOPTOSIS | - |
| dc.subject | CELL REMODELLING | - |
| dc.subject | APOPTOTIC PATHWAYS | - |
| dc.subject | Otras Producción Animal y Lechería | - |
| dc.subject | Producción Animal y Lechería | - |
| dc.subject | CIENCIAS AGRÍCOLAS | - |
| dc.subject | Otras Ciencias Veterinarias | - |
| dc.subject | Ciencias Veterinarias | - |
| dc.subject | CIENCIAS AGRÍCOLAS | - |
| dc.title | Cellular Remodelling by Apoptosis During Porcine Placentation | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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