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dc.creatorSimonetti, Sebastián Osvaldo-
dc.creatorLarghi, Enrique Leandro-
dc.creatorKaufman, Teodoro Saul-
dc.date2018-07-20T16:11:35Z-
dc.date2018-07-20T16:11:35Z-
dc.date2016-12-
dc.date2018-07-18T20:49:32Z-
dc.date.accessioned2019-04-29T15:51:37Z-
dc.date.available2019-04-29T15:51:37Z-
dc.date.issued2016-12-
dc.identifierSimonetti, Sebastián Osvaldo; Larghi, Enrique Leandro; Kaufman, Teodoro Saul; The 3,4-dioxygenated 5-hydroxy-4-aryl-quinolin-2(1: H)-one alkaloids. Results of 20 years of research, uncovering a new family of natural products; Royal Society of Chemistry; Natural Product Reports; 33; 12; 12-2016; 1425-1446-
dc.identifier0265-0568-
dc.identifierhttp://hdl.handle.net/11336/52739-
dc.identifierCONICET Digital-
dc.identifierCONICET-
dc.identifier.urihttp://rodna.bn.gov.ar:8080/jspui/handle/bnmm/303942-
dc.descriptionCovering: up to April 2016 Aspergillus and Penicillium are fungal species known to produce a high diversity of secondary metabolites, many of them endowed with interesting bioactivity. The small but steadily growing family of the naturally occurring 5-hydroxy-4-aryl-quinolin-2(1H)-one alkaloids and closely related compounds, which represent the results of various research projects that spanned over 20 years and involved scientists from different continents, are covered here. Emphasis is placed on the isolation and chemical structures of the different compounds, together with their source microorganisms, environmental conditions, country or region of origin, and relevant biological activities. In addition, stereochemical aspects, as well as the proposed biosynthetic pathways for the different members, and the incipient synthetic efforts towards some of the compounds or their key intermediates, are discussed in detail.-
dc.descriptionFil: Simonetti, Sebastián Osvaldo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; Argentina-
dc.descriptionFil: Larghi, Enrique Leandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; Argentina-
dc.descriptionFil: Kaufman, Teodoro Saul. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; Argentina-
dc.formatapplication/pdf-
dc.formatapplication/pdf-
dc.formatapplication/pdf-
dc.formatapplication/pdf-
dc.languageeng-
dc.publisherRoyal Society of Chemistry-
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1039/C6NP00064A-
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://pubs.rsc.org/en/Content/ArticleLanding/2016/NP/C6NP00064A-
dc.rightsinfo:eu-repo/semantics/restrictedAccess-
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/-
dc.sourcereponame:CONICET Digital (CONICET)-
dc.sourceinstname:Consejo Nacional de Investigaciones Científicas y Técnicas-
dc.sourceinstacron:CONICET-
dc.subjectNATURAL PRODUCTS-
dc.subjectORGANIC SYNTHESIS-
dc.subjectQUINOLONES-
dc.subjectBIOLOGICAL ACTIVITY-
dc.subjectOtras Ciencias Químicas-
dc.subjectCiencias Químicas-
dc.subjectCIENCIAS NATURALES Y EXACTAS-
dc.titleThe 3,4-dioxygenated 5-hydroxy-4-aryl-quinolin-2(1: H)-one alkaloids. Results of 20 years of research, uncovering a new family of natural products-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.typeinfo:ar-repo/semantics/articulo-
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