Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Nikoloff, Noelia | - |
| dc.creator | Larramendy, Marcelo Luis | - |
| dc.creator | Soloneski, Sonia Maria Elsa | - |
| dc.date | 2018-01-10T19:01:15Z | - |
| dc.date | 2018-01-10T19:01:15Z | - |
| dc.date | 2014-10 | - |
| dc.date | 2018-01-10T16:51:34Z | - |
| dc.date.accessioned | 2019-04-29T15:52:31Z | - |
| dc.date.available | 2019-04-29T15:52:31Z | - |
| dc.date.issued | 2014-10 | - |
| dc.identifier | Soloneski, Sonia Maria Elsa; Larramendy, Marcelo Luis; Nikoloff, Noelia; Comparative EvaluationIn vitroof the HerbicideFlurochloridone by Cytokinesis-blockMicronucleus Cytome and Comet Assays; John Wiley & Sons Inc; Environmental Toxicology; 29; 8; 10-2014; 884-892 | - |
| dc.identifier | 1520-4081 | - |
| dc.identifier | http://hdl.handle.net/11336/32872 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/304337 | - |
| dc.description | Thein-vitroeffects of flurochloridone and its formulations Twin Pack Gold1(25% a.i.) andRainbow1(25% a.i.) were evaluated in Chinese Hamster Ovary K1 (CHO-K1) cells. The cytokinesis-blockmicronucleus cytome (CBMN-cyt) and single-cell gel electrophoresis (SCGE) assays were used. Theactivities were tested within the range of final concentrations of 0.25–15lg flurochloridone/mL. Theresults demonstrated that both the flurochloridone and Rainbow1were not able to induce micronuclei(MN). On the other hand, Twin Pack Gold1only increased the frequency of MN at 5lg/mL. Furthermore,10 and 15lg/mL of both formulations resulted in a cellular cytotoxicity demonstrated by alterations in thenuclear division index and cellular death. SCGE assay appeared to be a more sensitive bioassay fordetecting primary DNA strand breaks at lower concentrations of flurochloridone than MN did. A markedincrease in the genetic damage index was observed when 5 and 15lg/mL of both flurochloridone andRainbow1but only when 15lg/mL of Twin Pack Gold1were used. This is the first report demonstratingthat flurochloridone and its two commercial formulations are able to induce single-strand DNA breaksinvitroon mammalian cells. | - |
| dc.description | Fil: Nikoloff, Noelia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Cátedra de Citología; Argentina | - |
| dc.description | Fil: Larramendy, Marcelo Luis. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Cátedra de Citología; Argentina | - |
| dc.description | Fil: Soloneski, Sonia Maria Elsa. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Cátedra de Citología; Argentina | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | John Wiley & Sons Inc | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1002/tox.21816 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/tox.21816/abstract | - |
| dc.rights | info:eu-repo/semantics/restrictedAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.subject | flurochloridone | - |
| dc.subject | CBMN-cyt assay | - |
| dc.subject | DNA-single strands breaks | - |
| dc.subject | CHO-K1 cells | - |
| dc.subject | commercial formulations | - |
| dc.subject | Otras Ciencias Biológicas | - |
| dc.subject | Ciencias Biológicas | - |
| dc.subject | CIENCIAS NATURALES Y EXACTAS | - |
| dc.title | Comparative EvaluationIn vitroof the HerbicideFlurochloridone by Cytokinesis-blockMicronucleus Cytome and Comet Assays | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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