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dc.creatorBekinschtein, Pedro Alejandro-
dc.creatorKent, Brianne A.-
dc.creatorOomen, Charlotte-
dc.creatorGregory D. Clemenson-
dc.creatorFred H. Gage-
dc.creatorLisa M. Saksida-
dc.creatorTimothy J. Bussey-
dc.date2017-04-26T19:41:15Z-
dc.date2017-04-26T19:41:15Z-
dc.date2014-08-
dc.date2017-04-26T14:13:02Z-
dc.date.accessioned2019-04-29T15:53:37Z-
dc.date.available2019-04-29T15:53:37Z-
dc.date.issued2014-08-
dc.identifierBekinschtein, Pedro Alejandro; Kent, Brianne A.; Oomen, Charlotte; Gregory D. Clemenson; Fred H. Gage; et al.; Brain-derived neurotrophic factor interacts with adult-born immature cells in the dentate gyrus during consolidation of overlapping memories; Wiley; Hippocampus; 24; 8; 8-2014; 905-911-
dc.identifier1050-9631-
dc.identifierhttp://hdl.handle.net/11336/15763-
dc.identifier.urihttp://rodna.bn.gov.ar:8080/jspui/handle/bnmm/304836-
dc.descriptionSuccessful memory involves not only remembering information over time but also keeping memories distinct and less confusable. The computational process for making representations of similar input patterns more distinct from each other has been referred to as “pattern separation.” Although adult-born immature neurons have been implicated in this memory feature, the precise role of these neurons and associated molecules in the processing of overlapping memories is unknown. Recently, we found that brain-derived neurotrophic factor (BDNF) in the dentate gyrus is required for the encoding/consolidation of overlapping memories. In this study, we provide evidence that consolidation of these “pattern-separated” memories requires the action of BDNF on immature neurons specifically.-
dc.descriptionFil: Bekinschtein, Pedro Alejandro. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Biología Celular y Neurociencias; Argentina. University of Cambridge; Reino Unido. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina-
dc.descriptionFil: Kent, Brianne A.. University of Cambridge; Reino Unido-
dc.descriptionFil: Oomen, Charlotte. University of Cambridge; Reino Unido-
dc.descriptionFil: Gregory D. Clemenson. Salk Institute For Biological Studies; Estados Unidos-
dc.descriptionFil: Fred H. Gage. Salk Institute For Biological Studies; Estados Unidos-
dc.descriptionFil: Lisa M. Saksida. University of Cambridge; Reino Unido-
dc.descriptionFil: Timothy J. Bussey. University of Cambridge; Reino Unido-
dc.formatapplication/pdf-
dc.formatapplication/pdf-
dc.formatapplication/pdf-
dc.languageeng-
dc.publisherWiley-
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/hipo.22304/abstract-
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1002/hipo.22304-
dc.rightsinfo:eu-repo/semantics/openAccess-
dc.rightshttps://creativecommons.org/licenses/by/2.5/ar/-
dc.sourcereponame:CONICET Digital (CONICET)-
dc.sourceinstname:Consejo Nacional de Investigaciones Científicas y Técnicas-
dc.sourceinstacron:CONICET-
dc.subjectDENTATE GYRUS-
dc.subjectPATTERN SEPARATION-
dc.subjectNEUROGENESIS-
dc.subjectBDNF-
dc.subjectOtras Ciencias Biológicas-
dc.subjectCiencias Biológicas-
dc.subjectCIENCIAS NATURALES Y EXACTAS-
dc.titleBrain-derived neurotrophic factor interacts with adult-born immature cells in the dentate gyrus during consolidation of overlapping memories-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.typeinfo:ar-repo/semantics/articulo-
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