Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Rivadeneira, Josefina | - |
| dc.creator | Luz, Gisela M. | - |
| dc.creator | Audisio, Marcela Carina | - |
| dc.creator | Mano, Joao F. | - |
| dc.creator | Gorustovich Alonso, Alejandro Adrian | - |
| dc.date | 2017-08-10T19:43:22Z | - |
| dc.date | 2017-08-10T19:43:22Z | - |
| dc.date | 2015-10 | - |
| dc.date | 2016-12-16T16:41:27Z | - |
| dc.date.accessioned | 2019-04-29T15:55:58Z | - |
| dc.date.available | 2019-04-29T15:55:58Z | - |
| dc.identifier | Rivadeneira, Josefina; Luz, Gisela M.; Audisio, Marcela Carina; Mano, Joao F.; Gorustovich Alonso, Alejandro Adrian; Novel antibacterial bioactive glass nanocomposite functionalized with tetracycline hydrochloride; De Gruyter; Biomedical Glasses; 1; 1; 10-2015; 128-135 | - |
| dc.identifier | http://hdl.handle.net/11336/22135 | - |
| dc.identifier | 2299-3932 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/305648 | - |
| dc.description | To prevent the high frequency of wound infections, anti-bacterial agents can be loaded onto composites. In the present study, the antibiotic tetracycline hydrochloride (TC)was incorporated, for the first time, in collagen type I membranes coated with nano-sized SiO2-CaOP2O5 bioactive glass (n-BG) obtained by a sol-gel chemical route. Collagen membranes coated with n-BG were immersed in simulated body fluid (SBF) containing 0.25, 0.75 or 1.25 mg mL−1 of TC for 48 h at 37∘C following a coprecipitation method. The antibiotic was released in distilledwater at 37∘C for up to 72 h. The antibacterial activity of the composites was evaluated in vitro by the inhibition zone test and plate count method. Two different Staphylococcus aureus strains, S. aureus ATCC29213 and S. aureus ATCC25923, were exposed to the biomaterials. The results showed that the incorporation but not the release of TC was dependent on the initial concentration of TC in SBF. The biomaterials inhibited S. aureus growth, although the efficacy was similar for all the concentrations. The results allow us to conclude that the new composite could have potential in the prevention of wound infections. | - |
| dc.description | Fil: Rivadeneira, Josefina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Tecnologías y Ciencias de la Ingeniería "Hilario Fernández Long". Universidad de Buenos Aires. Facultad de Ingeniería. Instituto de Tecnologías y Ciencias de la Ingeniería "Hilario Fernández Long"; Argentina | - |
| dc.description | Fil: Luz, Gisela M.. Universidade Do Minho; Portugal | - |
| dc.description | Fil: Audisio, Marcela Carina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Investigaciones Para la Industria Química. Universidad Nacional de Salta. Facultad de Ingeniería. Instituto de Investigaciones Para la Industria Química; Argentina | - |
| dc.description | Fil: Mano, Joao F.. Universidade Do Minho; Portugal | - |
| dc.description | Fil: Gorustovich Alonso, Alejandro Adrian. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Tecnologías y Ciencias de la Ingeniería "Hilario Fernández Long". Universidad de Buenos Aires. Facultad de Ingeniería. Instituto de Tecnologías y Ciencias de la Ingeniería "Hilario Fernández Long"; Argentina | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | De Gruyter | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1515/bglass-2015-0012 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/https://www.degruyter.com/view/j/bglass.2015.1.issue-1/bglass-2015-0012/bglass-2015-0012.xml | - |
| dc.rights | info:eu-repo/semantics/openAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.subject | Bioactive glasses | - |
| dc.subject | Antibacterial activity | - |
| dc.subject | Nanocomposite | - |
| dc.subject | Bioquímica y Biología Molecular | - |
| dc.subject | Ciencias Biológicas | - |
| dc.subject | CIENCIAS NATURALES Y EXACTAS | - |
| dc.title | Novel antibacterial bioactive glass nanocomposite functionalized with tetracycline hydrochloride | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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