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| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.provenance | Comisión de Investigaciones Científicas | - |
| dc.contributor | Mendieta, Julieta Renée | - |
| dc.contributor | Fimognari, Carmela | - |
| dc.contributor | Daleo, Gustavo Raúl | - |
| dc.contributor | Hrelia, Patrizia | - |
| dc.contributor | Guevara, María G. | - |
| dc.creator | Mendieta, Julieta Renée | - |
| dc.creator | Fimognari, Carmela | - |
| dc.creator | Daleo, Gustavo Raúl | - |
| dc.creator | Hrelia, Patrizia | - |
| dc.creator | Guevara, María G. | - |
| dc.date | 2010-10-13 | - |
| dc.date.accessioned | 2019-04-29T16:03:17Z | - |
| dc.date.available | 2019-04-29T16:03:17Z | - |
| dc.date.issued | 2010-10-13 | - |
| dc.identifier | http://digital.cic.gba.gob.ar/handle/11746/5364 | - |
| dc.identifier | Recurso Completo | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/308001 | - |
| dc.description | <em>St</em>APs are potato aspartic proteases with cytotoxic activity against plant pathogens and spermatozoa.<em>St</em>APs cytotoxic activity is selective, since these proteins do not exert toxic effect on plant cells and erythrocytes. In this work, we investigated the capacity of<em>St</em>APs to exert cytotoxicity on human leukaemia cells. Obtained results show that<em>St</em>APs induce apoptosis on Jurkat T cells after a short time of incubation in a dose-dependent manner. However, no significative effect on the T lymphocytes viability was observed at all<em>St</em>APs incubation times and concentrations tested. These results suggest that<em>St</em>APs can be conceptually promising leads for cancer therapy. | - |
| dc.format | application/pdf | - |
| dc.format | 7 p. | - |
| dc.language | eng | - |
| dc.rights | info:eu-repo/semantics/openAccess | - |
| dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International (BY-NC-ND 4.0) | - |
| dc.source | reponame:CIC Digital (CICBA) | - |
| dc.source | instname:Comisión de Investigaciones Científicas de la Provincia de Buenos Aires | - |
| dc.source | instacron:CICBA | - |
| dc.source.uri | http://digital.cic.gba.gob.ar/handle/11746/5364 | - |
| dc.source.uri | Recurso Completo | - |
| dc.subject | Biología Celular, Microbiología | - |
| dc.title | Cytotoxic effect of potato aspartic proteases (StAPs) on Jurkat T cells | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/submittedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | Comisión de Investigaciones Científicas de la Prov. de Buenos Aires | |
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