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Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.provenance | Comisión de Investigaciones Científicas | - |
dc.contributor | McCarthy, Antonio Desmond | - |
dc.contributor | Etcheverry, Susana B. | - |
dc.contributor | Bruzzone, Liliana | - |
dc.contributor | Cortizo, Ana María | - |
dc.creator | McCarthy, Antonio Desmond | - |
dc.creator | Etcheverry, Susana B. | - |
dc.creator | Bruzzone, Liliana | - |
dc.creator | Cortizo, Ana María | - |
dc.date | 1997 | - |
dc.date.accessioned | 2019-04-29T16:06:24Z | - |
dc.date.available | 2019-04-29T16:06:24Z | - |
dc.date.issued | 1997 | - |
dc.identifier | http://digital.cic.gba.gob.ar/handle/11746/4899 | - |
dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/309330 | - |
dc.description | Two different lines of osteoblast-like cells were used to investigate the effect of advanced glycation end-products of bovine serum albumin on cell proliferation and differentiation. These parameters were found to be both dose- and time-dependent. Cell proliferation remained unchanged after a 24 h incubation period, it increased after intermediate periods of incubation with advanced glycation end-products, but was found to be depressed after several days incubation. Cellular alkaline phosphatase activity followed a similar pattern: an initial increase induced by advanced glycation end-products was generally followed, after relatively long incubation periods, by a slight but significant decrease in this parameter. 45Ca2+ uptake was only significantly inhibited by advanced glycation end-products after 24 h incubation. These results suggest that advanced glycation end-products directly regulate osteoblast proliferation and differentiation in a dose and time dependent manner. | - |
dc.format | application/pdf | - |
dc.format | 9 p. | - |
dc.language | spa | - |
dc.rights | info:eu-repo/semantics/openAccess | - |
dc.rights | Attribution 4.0 International (BY 4.0) | - |
dc.source | reponame:CIC Digital (CICBA) | - |
dc.source | instname:Comisión de Investigaciones Científicas de la Provincia de Buenos Aires | - |
dc.source | instacron:CICBA | - |
dc.source.uri | http://digital.cic.gba.gob.ar/handle/11746/4899 | - |
dc.subject | Ciencias Químicas | - |
dc.title | Effects of advanced glycation end-products on the proliferation and differentiation of osteoblast-like cells | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/submittedVersion | - |
dc.type | info:ar-repo/semantics/articulo | - |
Aparece en las colecciones: | Comisión de Investigaciones Científicas de la Prov. de Buenos Aires |
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