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dc.provenanceComisión de Investigaciones Científicas-
dc.contributorFernandez, María Belén-
dc.contributorDaleo, Gustavo Raúl-
dc.contributorGuevaRA, María Gabriela-
dc.creatorFernandez, María Belén-
dc.creatorDaleo, Gustavo Raúl-
dc.creatorGuevaRA, María Gabriela-
dc.date2015-01-20-
dc.date.accessioned2019-04-29T16:13:54Z-
dc.date.available2019-04-29T16:13:54Z-
dc.date.issued2015-01-20-
dc.identifierhttp://digital.cic.gba.gob.ar/handle/11746/5361-
dc.identifier.urihttp://rodna.bn.gov.ar:8080/jspui/handle/bnmm/312143-
dc.descriptionPlant proteases with caspase-like enzymatic activity have been widely studied during the last decade. Previously, we have reported the presence and induction of caspase-3 like activity in the apoplast of potato leaves during <em>Solanum tuberosum- Phytophthora infestans</em> interaction. In this work we have purified and identified a potato extracellular protease with caspase-3 like enzymatic activity from potato leaves infected with <em>P. infestans.</em> Results obtained from the size exclusion chromatography show that the isolated protease is a monomeric enzyme with an estimated molecular weight of 70 kDa approximately. Purified protease was analyzed by MALDI-TOF MS, showing a 100% of sequence identity with the deduced amino acid sequence of a putative subtilisin-like protease from <em>S. tuberosum </em>(Solgenomics protein ID: PGSC0003DMP400018521). For this reason the isolated protease was named as StSBTc-3. This report constitutes the first evidence of isolation and identification of a plant subtilisin-like protease with caspase-3 like enzymatic activity. In order to elucidate the possible function of StSBTc-3 during plant pathogen interaction, we demonstrate that like animal caspase-3, StSBTc-3 is able to produce in vitro cytoplasm shrinkage in plant cells and to induce plant cell death. This result suggest that, StSBTc-3 could exert a caspase executer function during potato- <em>P. infestans</em> interaction, resulting in the restriction of the pathogen spread during plantepathogen interaction.-
dc.formatapplication/pdf-
dc.format10 p.-
dc.languageeng-
dc.rightsinfo:eu-repo/semantics/openAccess-
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International (BY-NC-ND 4.0)-
dc.sourcereponame:CIC Digital (CICBA)-
dc.sourceinstname:Comisión de Investigaciones Científicas de la Provincia de Buenos Aires-
dc.sourceinstacron:CICBA-
dc.source.urihttp://digital.cic.gba.gob.ar/handle/11746/5361-
dc.subjectBiología Celular, Microbiología-
dc.titleIsolation and characterization of a Solanum tuberosum subtilisin-like protein with caspase-3 activity (StSBTc-3)-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/submittedVersion-
dc.typeinfo:ar-repo/semantics/articulo-
Aparece en las colecciones: Comisión de Investigaciones Científicas de la Prov. de Buenos Aires

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