Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.provenance | Universidad Nacional de Rosario.RepHipUNR | - |
| dc.creator | Pergomet, Jorgelina Leonor | - |
| dc.creator | Kaufman, Teodoro Saúl | - |
| dc.creator | Bracca, Andrea Beatriz Juana | - |
| dc.date | 2016-05-17 | - |
| dc.date | 2016-05-17 | - |
| dc.date.accessioned | 2019-07-15T19:05:05Z | - |
| dc.date.available | 2019-07-15T19:05:05Z | - |
| dc.date.issued | 2016-05-17 | - |
| dc.date.issued | 2016-05-17 | - |
| dc.identifier | 0018-019X | - |
| dc.identifier | http://hdl.handle.net/2133/10498 | - |
| dc.identifier | http://hdl.handle.net/2133/10498 | - |
| dc.identifier.uri | http://rodna.bn.gov.ar/jspui/handle/bnmm/570840 | - |
| dc.description | A straightforward approach toward 6-bromo-2-isopropylidenecoumaranone, a potential intermediate toward alkaloid TMC 120-B, pseudodeflectusin, and other natural products, was reported. The synthetic sequence involved the reaction of 3-bromosalicylaldehyde with chloroacetone and cyclization of the resulting ether to a 2-acetylcoumaranol intermediate. This was followed by sequential methyl Grignard addition and Jones’ oxidation to the corresponding coumaranone, which was dehydrated to the final product with the methanesulfonyl chloride/pyridine reagent. The protection of the coumaranol as the corresponding THP-ether resulted in improved product yields. | - |
| dc.description | Fil: Pergomet, Jorgelina Leonor. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario (IQUIR-CONICET); Argentina. | - |
| dc.description | Fil: Kaufman, Teodoro Saúl. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario (IQUIR-CONICET); Argentina. | - |
| dc.description | Fil: Bracca, Andrea Beatriz Juana. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario (IQUIR-CONICET); Argentina. | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Wiley | - |
| dc.relation | http://onlinelibrary.wiley.com/doi/10.1002/hlca.201500525/abstract | - |
| dc.relation | http://dx.doi.org/doi:10.1002/hlca.201500525 | - |
| dc.rights | info:eu-repo/semantics/openAccess | - |
| dc.source | reponame:RepHipUNR (UNR) | - |
| dc.source | instname:Universidad Nacional de Rosario | - |
| dc.source | instacron:UNR | - |
| dc.source.uri | http://hdl.handle.net/2133/10498 | - |
| dc.subject | 6-Bromo-2-isopropylidenecoumaranone | - |
| dc.subject | TMC-120B | - |
| dc.subject | Pseudodeflectusin | - |
| dc.subject | Natural Product Synthesis | - |
| dc.subject | Prolinemediated Cyclization | - |
| dc.title | Expedient approach to 6-bromo-2-isopropylidenecoumaranone, a potential intermediate for the synthesis of TMC-120B, pseudodeflectusin, and Their congeners | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | artículo | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | Universidad Nacional de Rosario. RepHipUNR | |
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