Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.provenance | Universidad Nacional de Rosario.RepHipUNR | - |
| dc.creator | Marzi, Marta Mónica | - |
| dc.creator | Weitz, Darío | - |
| dc.creator | Avila, Aylén | - |
| dc.creator | Molina, Gabriel | - |
| dc.creator | Caraballo, Lucía | - |
| dc.creator | Piskulic, Laura | - |
| dc.date | 2015-01 | - |
| dc.date | 2015-01 | - |
| dc.date.accessioned | 2019-07-15T19:05:23Z | - |
| dc.date.available | 2019-07-15T19:05:23Z | - |
| dc.date.issued | 2015-01 | - |
| dc.date.issued | 2015-01 | - |
| dc.identifier | 0034-9887 | - |
| dc.identifier | http://hdl.handle.net/2133/10526 | - |
| dc.identifier | http://hdl.handle.net/2133/10526 | - |
| dc.identifier.uri | http://rodna.bn.gov.ar/jspui/handle/bnmm/570870 | - |
| dc.description | Background: Domperidone is widely prescribed in patients with gastrointestinal disorders but some cardiac adverse effects have been recently reported. Aim: To evaluate the risk of QT prolongation, ventricular arrhythmias and sudden cardiac death associated with the use of oral domperidone in adults without cancer. Material and Methods: Systematic searches in MEDLINE, LILACS, SciELO, the Cochrane Library and regulatory agencies websites were performed, followed by a manual search of cited references. The search strategy consisted of combining free and indexed text words without any date or language restriction. Results: Three case-control studies met the inclusion criteria; none of them evaluated QT interval prolongation. With low risk of bias, each study quantified the risk of ventricular arrhythmia or sudden cardiac death (VA/SCD). The odds ratios for these events in these studies were 4.7 (95% confidence interval (CI): 1.4-16), 1.59 (95% CI: 1.28-1.98) and 11.02 (95% CI: 2.02-62.3) respectively. A significantly increased risk was observed in patients older than 60 years of age or receiving doses > 30 mg/day. Conclusions: Heterogeneity between selected studies did not allow the computation of a summary measure. However, evidence was found that an increased risk of VA/SCD is associated with the use of oral domperidone in adults. | - |
| dc.description | Fil: Marzi, Marta Mónica. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Matemática y Estadística; Argentina. | - |
| dc.description | Fil: Weitz, Darío. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Matemática y Estadística; Argentina. | - |
| dc.description | Fil: Avila, Aylén. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Matemática y Estadística; Argentina. | - |
| dc.description | Fil: Molina, Gabriel. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Matemática y Estadística; Argentina. | - |
| dc.description | Fil: Caraballo, Lucía. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Matemática y Estadística; Argentina. | - |
| dc.description | Fil: Piskulic, Laura. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Matemática y Estadística; Argentina. | - |
| dc.format | application/pdf | - |
| dc.language | spa | - |
| dc.publisher | Sociedad Médica de Santiago | - |
| dc.relation | http://dx.doi.org/10.4067/S0034-98872015000100002 | - |
| dc.relation | http://www.revistamedicadechile.cl/ojs/index.php/rmedica/article/view/3594 | - |
| dc.rights | info:eu-repo/semantics/openAccess | - |
| dc.source | reponame:RepHipUNR (UNR) | - |
| dc.source | instname:Universidad Nacional de Rosario | - |
| dc.source | instacron:UNR | - |
| dc.source.uri | http://hdl.handle.net/2133/10526 | - |
| dc.subject | Arrhythmias, Cardiac | - |
| dc.subject | Domperidone | - |
| dc.subject | Long QT | - |
| dc.subject | Review | - |
| dc.subject | Arritmias Cardíacas | - |
| dc.subject | Domperidona | - |
| dc.title | Efectos adversos cardíacos de la domperidona en pacientes adultos : revisión sistemática | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | artículo | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | Universidad Nacional de Rosario. RepHipUNR | |
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